Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 1/20 | 0.60 |
| ▸ | CCR1 | P32246 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | CCR5 | P51681 | 1/20 | 0.54 |
| ▸ | PARP1 | P09874 | 1/20 | 0.51 |
| ▸ | GLO1 | Q04760 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14988789 | 1.00 | METAP2 (0.60) | METAP2CCR1RAB9ACCR5PARP1 | |
| SCHEMBL29955883 | 0.80 | METAP2 (0.41) | METAP2CCR1CCR5PARP1CYP1A2 | |
| 8-Hydroxy Quinaldine SCHEMBL28797391 | 0.78 | METAP2 (0.89) | METAP2CCR1RAB9ACCR5PARP1 | |
| 8-Hydroxy Quinaldine SCHEMBL29064778 | 0.78 | METAP2 (0.89) | METAP2CCR1RAB9ACCR5PARP1 | |
| SCHEMBL18340809 | 0.78 | NCF1 (0.58) | — | |
| SCHEMBL3141987 | 0.76 | MTNR1A (0.47) | TDP1 | |
| SCHEMBL2856863 | 0.75 | METAP2 (0.59) | METAP2CCR1RAB9ACCR5PARP1 | |
| 8-Hydroxy Quinaldine SCHEMBL297247 | 0.75 | METAP2 (1.00) | METAP2CCR1RAB9ACCR5PARP1 | |
| 8-Hydroxy Quinaldine SCHEMBL29483489 | 0.75 | METAP2 (1.00) | METAP2CCR1RAB9ACCR5PARP1 | |
| SCHEMBL12260616 | 0.74 | CCR1 (0.52) | METAP2CCR1RAB9ACCR5PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |