Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | CRHBP | P24387 | 1/20 | 0.45 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15959921 | 0.82 | KDM4E (0.65) | POLBMAPTKDM4ERAB9AKMT2A | |
| SCHEMBL15959922 | 0.77 | POLB (0.53) | POLBMAPTKDM4ERAB9AKMT2A | |
| SCHEMBL28165403 | 0.76 | L3MBTL1 (0.54) | POLBMAPTKDM4ERAB9ANPC1 | |
| SCHEMBL29771433 | 0.74 | POLB (1.00) | POLBMAPTKDM4ERAB9AKMT2A | |
| SCHEMBL29787117 | 0.74 | POLB (1.00) | POLBMAPTKDM4ERAB9AKMT2A | |
| SCHEMBL153365 | 0.74 | POLB (1.00) | POLBMAPTKDM4ERAB9AKMT2A | |
| SCHEMBL28165405 | 0.73 | KMT2A (0.53) | MAPTKDM4EKMT2ATDP1ALDH1A1 | |
| SCHEMBL28433232 | 0.73 | HTT (0.42) | POLBMAPTKDM4ERAB9AKMT2A | |
| SCHEMBL28441990 | 0.73 | ALDH1A1 (0.46) | POLBMAPTKDM4ERAB9AKMT2A | |
| SCHEMBL28438215 | 0.72 | POLB (0.43) | POLBMAPTRAB9AKMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |