Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 7/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.54 |
| ▸ | ATM | Q13315 | 4/20 | 0.54 |
| ▸ | GPR3 | P46089 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | XBP1 | P17861 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.47 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 5/20 | 0.47 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.47 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | NQO2 | P16083 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1092376 | 0.79 | L3MBTL1 (0.55) | L3MBTL1TDP1ATMGPR3NPSR1 | |
| SCHEMBL28236134 | 0.78 | L3MBTL1 (0.54) | L3MBTL1TDP1ATMGPR3NPSR1 | |
| SCHEMBL26631768 | 0.78 | TDP1 (0.54) | L3MBTL1TDP1ATMGPR3NPSR1 | |
| SCHEMBL14222653 | 0.78 | L3MBTL1 (0.54) | L3MBTL1TDP1ATMGPR3NPSR1 | |
| SCHEMBL28444190 | 0.77 | LMNA (0.40) | L3MBTL1TDP1ATMNPSR1MAPT | |
| SCHEMBL28438215 | 0.77 | POLB (0.43) | L3MBTL1TDP1ATMNPSR1MAPT | |
| SCHEMBL28165051 | 0.77 | ALDH1A1 (0.51) | L3MBTL1TDP1NPSR1MAPTSMN1; SMN2 | |
| SCHEMBL29957670 | 0.76 | POLB (0.58) | L3MBTL1TDP1NPSR1MAPTALDH1A1 | |
| SCHEMBL4200546 | 0.76 | BRPF1 (0.39) | L3MBTL1TDP1ATMNPSR1MAPT | |
| SCHEMBL28165405 | 0.75 | KMT2A (0.53) | L3MBTL1TDP1ATMMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| CN-106928121-B | High-efficiency preparation method of 3-substituted-benzo five-membered heterocycle-2-carbonyl compound | 暨南大学 | 2020-05-12 | — | — | CN | disclosed |
| CN-107635961-A | Indoles analog and its application method as 5 oxo ETE receptor antagonists | 皇家学习促进学会/麦吉尔大学 | 2018-01-26 | — | — | CN | disclosed |
| CN-106928121-A | The high efficiency preparation method of 3- substitution-benzo five-membered heterocycle -2- carbonyls | 暨南大学 | 2017-07-07 | — | — | CN | disclosed |