Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1942294 | 0.81 | ACHE (0.50) | — | |
| SCHEMBL4446207 | 0.78 | LIPG (0.37) | ALDH1A1KDM4ESMN1; SMN2LMNAGAA | |
| SCHEMBL21101670 | 0.75 | LIPG (0.41) | POLBALDH1A1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL7400838 | 0.75 | ALDH1A1 (0.47) | POLBGLAALDH1A1KDM4EMAPT | |
| SCHEMBL13348016 | 0.74 | POLB (0.47) | POLBGLAALDH1A1KDM4EMAPT | |
| SCHEMBL8633227 | 0.72 | POLB (0.71) | POLBGLAALDH1A1MAPTHRH3 | |
| SCHEMBL29957102 | 0.72 | CA1 (0.44) | ALDH1A1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL4450495 | 0.71 | ALDH1A1 (0.43) | POLBALDH1A1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL10747863 | 0.71 | POLB (0.44) | POLBGLAALDH1A1KDM4EMAPT | |
| SCHEMBL13312634 | 0.68 | POLB (0.42) | POLBGLAALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |