Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.33 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.32 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | PTGES | O14684 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29951339 | 0.88 | RORC (0.43) | POLBRORCALDH1A1PDE4BKAT2B | |
| SCHEMBL29953007 | 0.77 | KAT2B (0.43) | PDE4BKAT2BBAZ2BPDE4APDE4C | |
| SCHEMBL28753989 | 0.76 | RORC (0.40) | POLBRORCNPSR1MEN1MAPT | |
| SCHEMBL29333351 | 0.76 | POLB (0.47) | POLBALDH1A1 | |
| SCHEMBL29952250 | 0.76 | POLB (0.40) | POLBRORCALDH1A1NPC1RAB9A | |
| SCHEMBL24190659 | 0.76 | TDP1 (0.48) | POLBRORC | |
| SCHEMBL30396359 | 0.76 | TDP1 (0.48) | POLBRORC | |
| SCHEMBL21643931 | 0.75 | ALDH1A1 (0.44) | POLBRORCALDH1A1PDE4BL3MBTL1 | |
| SCHEMBL18031289 | 0.75 | MAPT (0.47) | ALDH1A1PDE4BNPC1RAB9AMAPT | |
| SCHEMBL29955501 | 0.74 | POLB (0.43) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |