SCHEMBL29957985

SCHEMBL29957985

C=C(CCNC(=O)CC#N)C(N)=O

nearest known ligand 0.52

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 5/20 0.52
ALDH1A1 P00352 4/20 0.33
CYP3A4 P08684 1/20 0.33
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA9 Q16790 1/20 0.32
MAPT P10636 3/20 0.32
HSD17B10 Q99714 2/20 0.32
LMNA P02545 2/20 0.32
HTT P42858 1/20 0.32
GAA P10253 1/20 0.31
KMT2A Q03164 1/20 0.31
KDM4E B2RXH2 1/20 0.30
TSHR P16473 1/20 0.30
GFER P55789 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6217575 0.76 MCL1 (0.74) MCL1ALDH1A1CYP3A4CA12CA1
SCHEMBL2126136 0.74 TDP1 (0.33) TSHR
SCHEMBL25197985 0.74
Ethylene SCHEMBL9786553 0.72 TDP1 (0.32) TSHR
SCHEMBL21315462 0.72
SCHEMBL1417241 0.72
SCHEMBL3911970 0.72 MCL1 (0.68) MCL1ALDH1A1CYP3A4CA12CA1
SCHEMBL7620131 0.72 MCL1 (0.68) MCL1ALDH1A1CYP3A4CA12CA1
SCHEMBL22803092 0.70 MCL1 (0.65) MCL1ALDH1A1CYP3A4CA12CA1
SCHEMBL413449 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12624214-B2 Polymerizable absorbers of UV and high energy visible light JOHNSON & JOHNSON VISION CARE, INC. (US) 2026-05-12 US disclosed
US-12595370-B2 Polymerizable absorbers of UV and high energy visible light JOHNSON & JOHNSON VISION CARE, INC. (US) 2026-04-07 US disclosed
US-20240067825-A1 POLYMERIZABLE ABSORBERS OF UV AND HIGH ENERGY VISIBLE LIGHT JOHNSON & JOHNSON VISION CARE (US) 2024-02-29 US disclosed
US-11820899-B2 Polymerizable absorbers of UV and high energy visible light JOHNSON & JOHNSON VISION CARE, INC. (US) 2023-11-21 US disclosed
EP-4219632-A2 POLYMERIZABLE ABSORBERS OF UV AND HIGH ENERGY VISIBLE LIGHT Johnson & Johnson Vision Care, Inc. (US) 2023-08-02 EP disclosed
CN-116355127-A Polymerizable absorbers for UV and high energy visible light 强生视力健公司 2023-06-30 CN disclosed
EP-3759171-B9 AN OPHTHALMIC DEVICE COMPRISING POLYMERIZABLE ABSORBERS OF UV AND HIGH ENERGY VISIBLE LIGHT JOHNSON & JOHNSON VISION CARE (US) 2023-05-24 EP disclosed
EP-3759171-B1 AN OPHTHALMIC DEVICE COMPRISING POLYMERIZABLE ABSORBERS OF UV AND HIGH ENERGY VISIBLE LIGHT JOHNSON & JOHNSON VISION CARE (US) 2023-02-22 EP disclosed
CN-111801389-B Polymerizable absorbers for UV and high energy visible light 强生视力健公司 2023-01-20 CN disclosed
US-20220340760-A1 POLYMERIZABLE ABSORBERS OF UV AND HIGH ENERGY VISIBLE LIGHT JOHNSON & JOHNSON VISION CARE, INC. 2022-10-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12595370-B2 Polymerizable absorbers of UV and high energy visible light NLRP3, NLRP1, XDH MCL1 4833/4885ALDH1A1 738/4885CYP3A4 19/4885
US-12624214-B2 Polymerizable absorbers of UV and high energy visible light CRY1, SCNN1G, MALT1 MCL1 4196/4885ALDH1A1 1349/4885CYP3A4 679/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.