Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | CA7 | P43166 | 2/20 | 0.45 |
| ▸ | CA9 | Q16790 | 2/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19893894 | 1.00 | TSHR (0.54) | TSHRPOLBSMN1; SMN2TDP1HPGD | |
| SCHEMBL29951307 | 0.87 | TSHR (0.54) | TSHRPOLBSMN1; SMN2TDP1HPGD | |
| SCHEMBL4628672 | 0.83 | TSHR (0.60) | TSHRPOLBSMN1; SMN2TDP1HPGD | |
| SCHEMBL473980 | 0.82 | MAPK1 (0.51) | TSHRHPGDKDM4EHSD17B10MEN1 | |
| SCHEMBL29952924 | 0.82 | MAPK1 (0.51) | TSHRHPGDKDM4EHSD17B10MEN1 | |
| SCHEMBL458104 | 0.81 | SLC6A4 (0.50) | TSHRSMN1; SMN2HPGDKDM4EMEN1 | |
| SCHEMBL29920551 | 0.81 | SLC6A4 (0.50) | TSHRSMN1; SMN2HPGDKDM4EMEN1 | |
| SCHEMBL30755337 | 0.81 | TSHR (0.57) | TSHRPOLBSMN1; SMN2TDP1HPGD | |
| SCHEMBL10562029 | 0.81 | TSHR (0.57) | TSHRPOLBSMN1; SMN2TDP1HPGD | |
| SCHEMBL1997075 | 0.81 | TSHR (0.60) | TSHRPOLBSMN1; SMN2TDP1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |