Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.48 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA7 | P43166 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL473980 | 1.00 | MAPK1 (0.51) | MAPK1TSHRMAOBALOX15KMT2A | |
| SCHEMBL19763606 | 0.90 | MAPK1 (0.46) | MAPK1TSHRMAOBALOX15KMT2A | |
| SCHEMBL6516041 | 0.89 | MAOB (0.51) | MAPK1TSHRMAOBALOX15KMT2A | |
| SCHEMBL235046 | 0.84 | TSHR (0.60) | MAPK1TSHRMAOBALOX15KMT2A | |
| SCHEMBL11225504 | 0.83 | CYP4F2 (0.67) | MAPK1TSHRALOX15KMT2AKDM4E | |
| SCHEMBL549144 | 0.83 | MAPK1 (0.54) | MAPK1TSHRMAOBALOX15KMT2A | |
| SCHEMBL29958024 | 0.82 | TSHR (0.54) | MAPK1TSHRKMT2AMEN1KDM4E | |
| SCHEMBL19893894 | 0.82 | TSHR (0.54) | MAPK1TSHRKMT2AMEN1KDM4E | |
| SCHEMBL27711843 | 0.81 | MAPK1 (0.47) | MAPK1TSHRMAOBALOX15KMT2A | |
| SCHEMBL19971601 | 0.81 | MAPK1 (0.52) | MAPK1TSHRMAOBALOX15KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |