Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 2/20 | 0.41 |
| ▸ | HTR1A | P08908 | 6/20 | 0.40 |
| ▸ | HTR1D | P28221 | 6/20 | 0.40 |
| ▸ | HTR1B | P28222 | 6/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA3 | P07451 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA6 | P23280 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.40 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12537785 | 0.86 | MCL1 (0.46) | MCL1LTA4HCA12CA1CA2 | |
| SCHEMBL29958075 | 0.79 | LTA4H (0.43) | MCL1LTA4HHTR1AHTR1BCA12 | |
| SCHEMBL1676909 | 0.79 | LTA4H (0.43) | MCL1LTA4HHTR1AHTR1BCA12 | |
| SCHEMBL9946081 | 0.77 | LTA4H (0.42) | LTA4HCA12CA1CA2CA3 | |
| SCHEMBL14474330 | 0.77 | MCL1 (0.46) | MCL1LTA4HCA12CA1CA2 | |
| SCHEMBL7784021 | 0.77 | NR5A1 (0.52) | MCL1LTA4HHTR1AHTR1DHTR1B | |
| SCHEMBL8405356 | 0.76 | LTA4H (0.43) | MCL1LTA4HCA12CA1CA2 | |
| SCHEMBL29955018 | 0.76 | LTA4H (0.43) | MCL1LTA4HCA12CA1CA2 | |
| SCHEMBL17175975 | 0.75 | THRA (0.45) | MCL1LTA4HCA12CA1CA2 | |
| SCHEMBL17802398 | 0.75 | TSHR (0.49) | MCL1LTA4HHTR1AHTR1DHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120149693-A1 | THERAPEUTIC COMPOUNDS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2012-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120149693-A1 | THERAPEUTIC COMPOUNDS | HTR2C, GRK2, GRK3 | MCL1 2648/4885LTA4H 1649/4885HTR1A 13/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.