Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP2 | O95551 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | TGM2 | P21980 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28890594 | 1.00 | TDP2 (0.50) | TDP2ALDH1A1MAPTL3MBTL1KDM4E | |
| SCHEMBL9201592 | 0.85 | TDP2 (0.50) | TDP2ALDH1A1MAPTL3MBTL1KDM4E | |
| SCHEMBL28087596 | 0.81 | ALDH1A1 (0.56) | TDP2ALDH1A1MAPTL3MBTL1KDM4E | |
| SCHEMBL9204538 | 0.81 | TDP2 (0.46) | TDP2ALDH1A1MAPTLMNAMEN1 | |
| SCHEMBL15313181 | 0.80 | TDP2 (0.43) | TDP2ALDH1A1MAPTL3MBTL1KDM4E | |
| SCHEMBL13295304 | 0.79 | TDP2 (0.49) | TDP2ALDH1A1MAPTL3MBTL1KDM4E | |
| SCHEMBL28890601 | 0.78 | TDP2 (0.40) | TDP2ALDH1A1MAPTL3MBTL1KDM4E | |
| SCHEMBL2776008 | 0.75 | KDM4E (0.42) | TDP2ALDH1A1MAPTL3MBTL1KDM4E | |
| SCHEMBL9705021 | 0.75 | KDM4E (0.42) | TDP2ALDH1A1MAPTL3MBTL1KDM4E | |
| SCHEMBL9204906 | 0.75 | TDP2 (0.40) | TDP2ALDH1A1HPGDTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115362155-B | Arylamine derivative, preparation method and medical application thereof | 中国医药研究开发中心有限公司 | 2024-06-18 | — | — | CN | disclosed |
| CN-115362155-A | Arylamine derivatives, and preparation method and medical application thereof | 中国医药研究开发中心有限公司 | 2022-11-18 | — | — | CN | disclosed |