SCHEMBL15313181

SCHEMBL15313181

CCOC(=O)C1C(=O)Nc2cc(Cl)c(F)cc2C1=O

nearest known ligand 0.67

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TDP2 O95551 1/20 0.43
ALDH1A1 P00352 4/20 0.38
MAPT P10636 2/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
KDM4E B2RXH2 4/20 0.38
HSD17B10 Q99714 2/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
GAA P10253 1/20 0.36
HPGD P15428 1/20 0.36
TP53 P04637 1/20 0.34
SMN1; SMN2 Q16637 3/20 0.34
TSHR P16473 2/20 0.34
POLB P06746 1/20 0.34
ALPL P05186 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29958253 0.80 TDP2 (0.50) TDP2ALDH1A1MAPTL3MBTL1KDM4E
SCHEMBL28890594 0.80 TDP2 (0.50) TDP2ALDH1A1MAPTL3MBTL1KDM4E
SCHEMBL9201592 0.80 TDP2 (0.50) TDP2ALDH1A1MAPTL3MBTL1KDM4E
SCHEMBL13295304 0.77 TDP2 (0.49) TDP2ALDH1A1MAPTL3MBTL1KDM4E
SCHEMBL9203839 0.76 TDP2 (0.43) TDP2ALDH1A1MAPTL3MBTL1KDM4E
SCHEMBL9203313 0.74 TDP2 (0.46) TDP2ALDH1A1MAPTL3MBTL1KDM4E
SCHEMBL28087596 0.74 ALDH1A1 (0.56) TDP2ALDH1A1MAPTL3MBTL1KDM4E
SCHEMBL14248069 0.74 LMNA (0.40) TDP2ALDH1A1MAPTL3MBTL1KDM4E
SCHEMBL9204538 0.71 TDP2 (0.46) TDP2ALDH1A1MAPTMEN1KMT2A
SCHEMBL9202279 0.71 GSK3B (0.48) TDP2MAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10150736-B2 Haptens and immunoreactive agents and use thereof for producing family antibodies and immunoassays for quinolones CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (CSIC) (ES) 2018-12-11 US disclosed
US-20130273581-A1 HAPTENS AND IMMUNOREACTIVE AGENTS AND USE THEREOF FOR PRODUCING FAMILY ANTIBODIES AND IMMUNOASSAYS FOR QUINOLONES CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (CSIC) (ES) 2013-10-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130273581-A1 HAPTENS AND IMMUNOREACTIVE AGENTS AND USE THEREOF FOR PRODUCING FAMILY ANTIBODIES AND IMMUNOASSAYS FOR QUINOLONES NQO2, NISCH, VIP TDP2 4424/4885ALDH1A1 2214/4885MAPT 4204/4885
US-10150736-B2 Haptens and immunoreactive agents and use thereof for producing family antibodies and immunoassays for quinolones NQO2, NISCH, VIP TDP2 4424/4885ALDH1A1 2214/4885MAPT 4204/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.