Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | RPA1 | P27694 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.40 |
| ▸ | MARS1 | P56192 | 3/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CDK4 | P11802 | 1/20 | 0.38 |
| ▸ | CCND1 | P24385 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2561030 | 1.00 | LMNA (0.43) | LMNARPA1ALDH1A1TDP1OPRM1 | |
| SCHEMBL2552828 | 0.88 | HTT (0.46) | ALDH1A1TDP1OPRM1L3MBTL1NPSR1 | |
| SCHEMBL2561348 | 0.85 | MARS1 (0.36) | LMNAALDH1A1MARS1KMT2A | |
| SCHEMBL15333245 | 0.85 | LMNA (0.53) | LMNARPA1OPRM1PKML3MBTL1 | |
| SCHEMBL5768692 | 0.81 | LMNA (0.50) | LMNARPA1ALDH1A1MARS1CNR2 | |
| SCHEMBL15330896 | 0.81 | OPRL1 (0.41) | LMNAOPRM1PKML3MBTL1CDK4 | |
| SCHEMBL15332421 | 0.81 | LMNA (0.39) | LMNARPA1ALDH1A1TDP1OPRM1 | |
| SCHEMBL15331702 | 0.81 | LMNA (0.41) | LMNARPA1OPRM1PKML3MBTL1 | |
| SCHEMBL15333179 | 0.81 | SMN1; SMN2 (0.43) | LMNAALDH1A1TDP1OPRM1PKM | |
| SCHEMBL2562419 | 0.79 | CNR2 (0.44) | LMNACDK4CCND1CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |