Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 7/20 | 0.40 |
| ▸ | CDK4 | P11802 | 1/20 | 0.40 |
| ▸ | CCND1 | P24385 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 5/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2562419 | 0.90 | CNR2 (0.44) | OPRL1LMNAKCNH2CNR2CDK4 | |
| SCHEMBL15331374 | 0.86 | OPRL1 (0.39) | OPRL1LMNAKCNH2CNR2OPRM1 | |
| SCHEMBL15330760 | 0.83 | SMN1; SMN2 (0.46) | LMNACNR2CDK4CCND1CNR1 | |
| SCHEMBL15333245 | 0.82 | LMNA (0.53) | LMNACNR2CDK4CCND1OPRM1 | |
| SCHEMBL29958261 | 0.81 | LMNA (0.43) | LMNACNR2CDK4CCND1OPRM1 | |
| SCHEMBL2561030 | 0.81 | LMNA (0.43) | LMNACNR2CDK4CCND1OPRM1 | |
| SCHEMBL15330993 | 0.80 | MAPT (0.41) | LMNA | |
| SCHEMBL2557394 | 0.80 | CDK4 (0.39) | LMNACNR2CDK4CCND1OPRM1 | |
| SCHEMBL15331454 | 0.80 | KMT2A (0.47) | LMNA | |
| SCHEMBL2553923 | 0.79 | L3MBTL1 (0.38) | CNR2OPRM1CNR1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| US-11225655-B2 | Bi-functional complexes and methods for making and using such complexes | NUEVOLUTION A/S (DK) | 2022-01-18 | — | — | US | disclosed |
| EP-3540059-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2019-09-18 | — | — | EP | disclosed |
| EP-2558577-B1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION AS (DK) | 2018-12-12 | — | — | EP | disclosed |
| US-20130281324-A1 | BI-FUNCTINAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2013-10-24 | — | — | US | disclosed |