Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 2/20 | 0.53 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.39 |
| ▸ | APBA1 | Q02410 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29956563 | 0.98 | CTSK (0.55) | CTSKMAP4K4CNR1HCAR3KMT2A | |
| SCHEMBL29957838 | 0.97 | CTSK (0.49) | CTSKMAP4K4CNR1HCAR3KMT2A | |
| SCHEMBL29951353 | 0.93 | CTSK (0.44) | CTSKMAP4K4HCAR3KMT2AALDH1A1 | |
| SCHEMBL16334530 | 0.74 | CTSK (0.57) | CTSKMAP4K4CNR1KMT2AKDM4E | |
| SCHEMBL13915436 | 0.74 | ALDH1A1 (0.60) | CTSKMAP4K4KMT2AKDM4EALDH1A1 | |
| SCHEMBL29956132 | 0.74 | CNR2 (0.42) | LMNASMN1; SMN2SYKCNR2FFAR4 | |
| SCHEMBL29632510 | 0.72 | CTSK (0.59) | CTSKMAP4K4KDM4EALDH1A1LMNA | |
| SCHEMBL29955535 | 0.72 | CNR2 (0.44) | SYKCNR2FFAR4 | |
| SCHEMBL29632728 | 0.72 | CTSK (0.59) | CTSKMAP4K4CNR1KMT2AKDM4E | |
| SCHEMBL4067162 | 0.71 | CTSK (0.50) | CTSKMAP4K4CNR1HCAR3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |