Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.65 |
| ▸ | MAOB | P27338 | 1/20 | 0.65 |
| ▸ | ACSL1 | P33121 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9261739 | 1.00 | MAOA (0.65) | MAOAMAOBACSL1RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL5352578 | 0.96 | MAOA (0.61) | MAOAMAOBACSL1RAB9ASMN1; SMN2 | |
| SCHEMBL30422589 | 0.90 | MAOA (0.46) | MAOAMAOBRAB9ASMN1; SMN2LMNA | |
| SCHEMBL1611188 | 0.90 | MAOA (0.46) | MAOAMAOBRAB9ASMN1; SMN2LMNA | |
| SCHEMBL10463267 | 0.90 | MAOA (0.52) | MAOAMAOBACSL1RAB9ASMN1; SMN2 | |
| SCHEMBL28889921 | 0.89 | MAOB (0.65) | MAOAMAOBACSL1RAB9ASMN1; SMN2 | |
| SCHEMBL13199306 | 0.86 | MAOA (0.45) | MAOAMAOBACSL1RAB9ASMN1; SMN2 | |
| SCHEMBL19821087 | 0.85 | MAOA (0.48) | MAOAMAOBRAB9ASMN1; SMN2LMNA | |
| Xanthene SCHEMBL27961423 | 0.82 | MAOA (0.74) | MAOAMAOBACSL1RAB9ASMN1; SMN2 | |
| SCHEMBL9455528 | 0.81 | MAOA (0.81) | MAOAMAOBACSL1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12595370-B2 | Polymerizable absorbers of UV and high energy visible light | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2026-04-07 | — | — | US | disclosed |
| US-20220340760-A1 | POLYMERIZABLE ABSORBERS OF UV AND HIGH ENERGY VISIBLE LIGHT | JOHNSON & JOHNSON VISION CARE, INC. | 2022-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12595370-B2 | Polymerizable absorbers of UV and high energy visible light | NLRP3, NLRP1, XDH | MAOA 871/4885MAOB 472/4885ACSL1 4241/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.