Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 4/20 | 0.81 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.72 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.72 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.72 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.72 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.72 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.72 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.72 |
| ▸ | MEN1 | O00255 | 2/20 | 0.72 |
| ▸ | LMNA | P02545 | 2/20 | 0.72 |
| ▸ | TTR | P02766 | 2/20 | 0.72 |
| ▸ | POLB | P06746 | 2/20 | 0.72 |
| ▸ | MMP2 | P08253 | 2/20 | 0.72 |
| ▸ | MAPT | P10636 | 2/20 | 0.72 |
| ▸ | THRB | P10828 | 2/20 | 0.72 |
| ▸ | MMP9 | P14780 | 2/20 | 0.72 |
| ▸ | HPGD | P15428 | 2/20 | 0.72 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4607871 | 1.00 | LCK (0.81) | LCKKDM4EALOX5CYP3A4ALDH1A1 | |
| SCHEMBL4607867 | 1.00 | LCK (0.81) | LCKKDM4EALOX5CYP3A4ALDH1A1 | |
| SCHEMBL30631591 | 0.90 | LCK (1.00) | LCKKDM4EALOX5CYP3A4ALDH1A1 | |
| SCHEMBL31706727 | 0.90 | LCK (1.00) | LCKKDM4EALOX5CYP3A4ALDH1A1 | |
| SCHEMBL1824175 | 0.90 | LCK (1.00) | LCKKDM4EALOX5CYP3A4ALDH1A1 | |
| SCHEMBL1824176 | 0.90 | LCK (1.00) | LCKKDM4EALOX5CYP3A4ALDH1A1 | |
| SCHEMBL10335571 | 0.87 | LCK (0.94) | LCKKDM4EALOX5CYP3A4ALDH1A1 | |
| SCHEMBL4608757 | 0.84 | PTGS2 (0.54) | LCKKDM4EALOX5CYP3A4ALDH1A1 | |
| SCHEMBL4608754 | 0.84 | PTGS2 (0.54) | LCKKDM4EALOX5CYP3A4ALDH1A1 | |
| SCHEMBL1932873 | 0.84 | LCK (0.91) | LCKKDM4EALOX5CYP3A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4313010-A1 | COMPOUNDS FOR USE IN THE TREATMENT AND PREVENTION OF COVID- 19 | Szekeres, Thomas (AT) | 2024-02-07 | — | — | EP | claimed |
| WO-2022200086-A1 | COMPOUNDS FOR USE IN THE TREATMENT AND PREVENTION OF COVID- 19 | SZEKERES THOMAS (AT) | 2022-09-29 | — | — | WO | claimed |
| EP-4313010-A1 | COMPOUNDS FOR USE IN THE TREATMENT AND PREVENTION OF COVID- 19 | Szekeres, Thomas (AT) | 2024-02-07 | — | — | EP | disclosed |
| WO-2022200086-A1 | COMPOUNDS FOR USE IN THE TREATMENT AND PREVENTION OF COVID- 19 | SZEKERES THOMAS (AT) | 2022-09-29 | — | — | WO | disclosed |