SCHEMBL4607871

SCHEMBL4607871

Oc1ccc(C=Cc2cc(O)c(O)c(O)c2)cc1O

nearest known ligand 0.81

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LCK P06239 4/20 0.81
KDM4E B2RXH2 4/20 0.72
ALOX5 P09917 3/20 0.72
CYP3A4 P08684 3/20 0.72
ALDH1A1 P00352 3/20 0.72
HSD17B10 Q99714 3/20 0.72
ALOX12 P18054 2/20 0.72
CYP2C9 P11712 2/20 0.72
HIF1A Q16665 2/20 0.72
MEN1 O00255 2/20 0.72
LMNA P02545 2/20 0.72
TTR P02766 2/20 0.72
POLB P06746 2/20 0.72
MMP2 P08253 2/20 0.72
MAPT P10636 2/20 0.72
THRB P10828 2/20 0.72
MMP9 P14780 2/20 0.72
HPGD P15428 2/20 0.72
PMP22 Q01453 2/20 0.72
KMT2A Q03164 2/20 0.72

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29958569 1.00 LCK (0.81) LCKKDM4EALOX5CYP3A4ALDH1A1
SCHEMBL4607867 1.00 LCK (0.81) LCKKDM4EALOX5CYP3A4ALDH1A1
SCHEMBL30631591 0.90 LCK (1.00) LCKKDM4EALOX5CYP3A4ALDH1A1
SCHEMBL31706727 0.90 LCK (1.00) LCKKDM4EALOX5CYP3A4ALDH1A1
SCHEMBL1824175 0.90 LCK (1.00) LCKKDM4EALOX5CYP3A4ALDH1A1
SCHEMBL1824176 0.90 LCK (1.00) LCKKDM4EALOX5CYP3A4ALDH1A1
SCHEMBL10335571 0.87 LCK (0.94) LCKKDM4EALOX5CYP3A4ALDH1A1
SCHEMBL4608757 0.84 PTGS2 (0.54) LCKKDM4EALOX5CYP3A4ALDH1A1
SCHEMBL4608754 0.84 PTGS2 (0.54) LCKKDM4EALOX5CYP3A4ALDH1A1
SCHEMBL1932873 0.84 LCK (0.91) LCKKDM4EALOX5CYP3A4ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4313010-A1 COMPOUNDS FOR USE IN THE TREATMENT AND PREVENTION OF COVID- 19 Szekeres, Thomas (AT) 2024-02-07 EP claimed
WO-2022200086-A1 COMPOUNDS FOR USE IN THE TREATMENT AND PREVENTION OF COVID- 19 SZEKERES THOMAS (AT) 2022-09-29 WO claimed
EP-1654210-B1 STILBENE DERIVATIVES AND THEIR USE IN MEDICAMENTS SZEKERES THOMAS (AT) 2008-07-30 EP claimed
US-20070191627-A1 Stilbene derivatives and their use in medicaments SZEKERES THOMAS 2007-08-16 US claimed
EP-1654210-A2 STILBENE DERIVATIVES AND THEIR USE IN MEDICAMENTS Szekeres, Thomas (AT) 2006-05-10 EP claimed
US-7026518-B2 Resveratrol analogs LAILA IMPEX (IN) 2006-04-11 US claimed
WO-2005102298-A1 MEDICAL SUBSTANCE MIXTURES CONTAINING RESVERATROL OR RESVERATROL-DERIVATIVES, IN ADDITION TO THE USE THEREOF IN THE PRODUCTION OF MEDICAMENTS SZEKERES THOMAS (AT) 2005-11-03 WO claimed
WO-2005016860-A2 STILBENE DERIVATIVES AND THEIR USE IN MEDICAMENTS SZEKERES THOMAS (AT) 2005-02-24 WO claimed
US-20040209951-A1 Novel resveratrol analogs LAILA IMPEX (IN) 2004-10-21 US claimed
EP-4313010-B1 COMPOUNDS FOR USE IN THE TREATMENT AND PREVENTION OF COVID- 19 SZEKERES THOMAS (AT) 2025-02-19 EP disclosed
US-20240166587-A1 SARS-CoV-2 inhibitors - artificial compounds SZEKERES THOMAS (AT) 2024-05-23 US disclosed
EP-4313010-A1 COMPOUNDS FOR USE IN THE TREATMENT AND PREVENTION OF COVID- 19 Szekeres, Thomas (AT) 2024-02-07 EP disclosed
WO-2022200086-A1 COMPOUNDS FOR USE IN THE TREATMENT AND PREVENTION OF COVID- 19 SZEKERES THOMAS (AT) 2022-09-29 WO disclosed
EP-1976487-A2 SUSTAINED RELEASE DOSAGE FORM OF PHENOTHIAZINE DERIVATIVES CONTAINING CHANNELIZER Astron Research Limited (IN) 2008-10-08 EP disclosed
US-20070191627-A1 Stilbene derivatives and their use in medicaments SZEKERES THOMAS 2007-08-16 US disclosed
WO-2007086079-A2 SUSTAINED RELEASE DOSAGE FORM OF PHENOTHIAZINE DERIVATIVES CONTAINING CHANNELIZER ASTRON RESEARCH LIMITED (IN) 2007-08-02 WO disclosed
EP-1654210-A2 STILBENE DERIVATIVES AND THEIR USE IN MEDICAMENTS Szekeres, Thomas (AT) 2006-05-10 EP disclosed
US-7026518-B2 Resveratrol analogs LAILA IMPEX (IN) 2006-04-11 US disclosed
WO-2005016860-A2 STILBENE DERIVATIVES AND THEIR USE IN MEDICAMENTS SZEKERES THOMAS (AT) 2005-02-24 WO disclosed
US-20040209951-A1 Novel resveratrol analogs LAILA IMPEX (IN) 2004-10-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240166587-A1 SARS-CoV-2 inhibitors - artificial compounds ACE2, ACE, FURIN LCK 3127/4885KDM4E 2886/4885ALOX5 2295/4885
US-20040209951-A1 Novel resveratrol analogs HRH1, CBR1, CBR3 LCK 4349/4885KDM4E 1415/4885ALOX5 1966/4885
US-20070191627-A1 Stilbene derivatives and their use in medicaments PTGS2, PTGS1, PTGER2 LCK 3040/4885KDM4E 3574/4885ALOX5 248/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.