SCHEMBL4608754

SCHEMBL4608754

Oc1cc(/C=C/c2cc(O)c(O)c(O)c2)cc(O)c1O

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 1/20 0.54
LCK P06239 5/20 0.53
CYP3A4 P08684 4/20 0.48
ALOX12 P18054 3/20 0.48
TP53 P04637 3/20 0.48
CYP2C9 P11712 3/20 0.48
ALOX15 P16050 3/20 0.48
THPO P40225 3/20 0.48
HIF1A Q16665 3/20 0.48
HSD17B10 Q99714 3/20 0.48
KDM4E B2RXH2 3/20 0.48
MEN1 O00255 3/20 0.48
ALDH1A1 P00352 3/20 0.48
LMNA P02545 3/20 0.48
MAPT P10636 3/20 0.48
HPGD P15428 3/20 0.48
KMT2A Q03164 3/20 0.48
SMN1; SMN2 Q16637 3/20 0.48
TDP1 Q9NUW8 3/20 0.48
RGS12 O14924 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4608757 1.00 PTGS2 (0.54) PTGS2LCKCYP3A4ALOX12TP53
SCHEMBL1393726 0.89 LCK (0.74) PTGS2LCKCYP3A4ALOX12TP53
SCHEMBL1393728 0.89 LCK (0.74) PTGS2LCKCYP3A4ALOX12TP53
SCHEMBL718527 0.84 PTGS1 (0.69) PTGS2LCKCYP3A4ALOX12TP53
3,4,5-Trihydroxy-Transstilbene SCHEMBL41160 0.84 PTGS2 (0.63) PTGS2LCKCYP3A4TP53HSD17B10
SCHEMBL718526 0.84 PTGS1 (0.69) PTGS2LCKCYP3A4ALOX12TP53
SCHEMBL5848709 0.84 TRPA1 (0.57) PTGS2LCKCYP3A4ALOX12TP53
3,4,5-Trihydroxy-Transstilbene SCHEMBL41159 0.84 PTGS2 (0.63) PTGS2LCKCYP3A4TP53HSD17B10
SCHEMBL4607871 0.84 LCK (0.81) PTGS2LCKCYP3A4ALOX12TP53
SCHEMBL15026081 0.84 PTGS1 (0.45) PTGS2LCKCYP3A4ALOX12TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4516298-A1 STILBENE COMPOUNDS FOR USE IN THE TREATMENT AND PREVENTION OF INFECTIONS WITH CYTOMEGALOVIRUS (CMV) Szekeres, Thomas (AT) 2025-03-05 EP claimed
EP-4313010-B1 COMPOUNDS FOR USE IN THE TREATMENT AND PREVENTION OF COVID- 19 SZEKERES THOMAS (AT) 2025-02-19 EP claimed
US-20240166587-A1 SARS-CoV-2 inhibitors - artificial compounds SZEKERES THOMAS (AT) 2024-05-23 US claimed
EP-4313010-A1 COMPOUNDS FOR USE IN THE TREATMENT AND PREVENTION OF COVID- 19 Szekeres, Thomas (AT) 2024-02-07 EP claimed
WO-2022200086-A1 COMPOUNDS FOR USE IN THE TREATMENT AND PREVENTION OF COVID- 19 SZEKERES THOMAS (AT) 2022-09-29 WO claimed
EP-1654210-B1 STILBENE DERIVATIVES AND THEIR USE IN MEDICAMENTS SZEKERES THOMAS (AT) 2008-07-30 EP claimed
US-20070191627-A1 Stilbene derivatives and their use in medicaments SZEKERES THOMAS 2007-08-16 US claimed
EP-1654210-A2 STILBENE DERIVATIVES AND THEIR USE IN MEDICAMENTS Szekeres, Thomas (AT) 2006-05-10 EP claimed
US-7026518-B2 Resveratrol analogs LAILA IMPEX (IN) 2006-04-11 US claimed
WO-2005016860-A2 STILBENE DERIVATIVES AND THEIR USE IN MEDICAMENTS SZEKERES THOMAS (AT) 2005-02-24 WO claimed
US-20040209951-A1 Novel resveratrol analogs LAILA IMPEX (IN) 2004-10-21 US claimed
WO-2004000302-A1 NOVEL RESVERATROL ANALOGS GOKARAJU GANGA RAJU (IN) 2003-12-31 WO claimed
WO-2026044308-A1 TREATMENT AND PREVENTION OF DISEASES CAUSED BY INFLUENZA VIRUS WITH 3,3',4,4',5,5'-HEXAHYDROXY-TRANS-STILBENE MEDIZINISCHE UNIVERSITÄT WIEN (AT) 2026-03-05 WO disclosed
EP-4678169-A1 COMPOUNDS FOR USE IN THE TREATMENT AND PREVENTION OF INFECTIONS WITH RSV Szekeres, Thomas (AT) 2026-01-14 EP disclosed
EP-4516298-A1 STILBENE COMPOUNDS FOR USE IN THE TREATMENT AND PREVENTION OF INFECTIONS WITH CYTOMEGALOVIRUS (CMV) Szekeres, Thomas (AT) 2025-03-05 EP disclosed
EP-4516298-A1 STILBENE COMPOUNDS FOR USE IN THE TREATMENT AND PREVENTION OF INFECTIONS WITH CYTOMEGALOVIRUS (CMV) Szekeres, Thomas (AT) 2025-03-05 EP disclosed
EP-1654210-A2 STILBENE DERIVATIVES AND THEIR USE IN MEDICAMENTS Szekeres, Thomas (AT) 2006-05-10 EP disclosed
US-7026518-B2 Resveratrol analogs LAILA IMPEX (IN) 2006-04-11 US disclosed
WO-2005016860-A2 STILBENE DERIVATIVES AND THEIR USE IN MEDICAMENTS SZEKERES THOMAS (AT) 2005-02-24 WO disclosed
US-20040209951-A1 Novel resveratrol analogs LAILA IMPEX (IN) 2004-10-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240166587-A1 SARS-CoV-2 inhibitors - artificial compounds ACE2, ACE, FURIN PTGS2 2681/4885LCK 3127/4885CYP3A4 124/4885
US-20040209951-A1 Novel resveratrol analogs HRH1, CBR1, CBR3 PTGS2 1161/4885LCK 4349/4885CYP3A4 1711/4885
US-20070191627-A1 Stilbene derivatives and their use in medicaments PTGS2, PTGS1, PTGER2 PTGS2 1/4885LCK 3040/4885CYP3A4 584/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.