Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | MME | P08473 | 6/20 | 0.54 |
| ▸ | ACE | P12821 | 5/20 | 0.54 |
| ▸ | CPA1 | P15085 | 2/20 | 0.54 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | CTSB | P07858 | 1/20 | 0.49 |
| ▸ | ALB | P02768 | 1/20 | 0.49 |
| ▸ | IL2 | P60568 | 1/20 | 0.49 |
| ▸ | MC4R | P32245 | 2/20 | 0.49 |
| ▸ | MC3R | P41968 | 2/20 | 0.49 |
| ▸ | MC1R | Q01726 | 2/20 | 0.49 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.48 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.48 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10054043 | 0.89 | CAPN1 (0.57) | CAPN1SLC6A2SLC6A4SLC6A3CTSB | |
| SCHEMBL2633261 | 0.87 | LMNA (0.68) | CAPN1LMNATDP1MMEITGB3 | |
| SCHEMBL14527567 | 0.86 | FCER2 (0.52) | CAPN1CTSBMC4RMC3RMC1R | |
| SCHEMBL14527561 | 0.85 | BDKRB2 (0.49) | CAPN1MMEACECPA1ACE2 | |
| SCHEMBL26993357 | 0.85 | LMNA (0.77) | CAPN1LMNATDP1MMEACE | |
| SCHEMBL14527547 | 0.85 | CAPN1 (0.58) | CAPN1CTSBMC4RMC3RMC1R | |
| SCHEMBL14527656 | 0.85 | PLG (0.53) | CAPN1CTSBMC4RMC3RMC1R | |
| SCHEMBL14527548 | 0.85 | CAPN1 (0.48) | CAPN1MMEACECPA1ACE2 | |
| SCHEMBL14288708 | 0.85 | CAPN1 (0.48) | CAPN1MMEACECPA1ACE2 | |
| SCHEMBL14527603 | 0.83 | CAPN1 (0.54) | CAPN1LMNACTSBMC4RMC3R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230330187-A1 | USE OF GHRELIN OR GHRELIN VARIANT FOR INCREASING DOSE INTENSITY OF CHEMOTHERAPEUTIC AGENTS IN PATIENTS WITH CANCER | OXEIA BIOPHARMACEUTICALS INC (US) | 2023-10-19 | — | — | US | disclosed |
| WO-2022226116-A1 | GHRELIN TREATMENT OF BRAIN DYSFUNCTION DUE TO VIRAL INFECTION | OXEIA BIOPHARMACEUTICALS, INC. (US) | 2022-10-27 | — | — | WO | disclosed |