Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 4/20 | 0.57 |
| ▸ | FCER2 | P06734 | 2/20 | 0.51 |
| ▸ | CTSB | P07858 | 1/20 | 0.51 |
| ▸ | MC1R | Q01726 | 4/20 | 0.50 |
| ▸ | MC4R | P32245 | 2/20 | 0.50 |
| ▸ | MC3R | P41968 | 2/20 | 0.50 |
| ▸ | MC5R | P33032 | 2/20 | 0.48 |
| ▸ | PLG | P00747 | 1/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | HTR3A | P46098 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14527547 | 0.93 | CAPN1 (0.58) | CAPN1FCER2CTSBMC1RMC4R | |
| SCHEMBL26002538 | 0.89 | CAPN1 (0.58) | CAPN1FCER2CTSBMC1RMC5R | |
| SCHEMBL29958699 | 0.89 | CAPN1 (0.55) | CAPN1CTSBMC1RMC4RMC3R | |
| SCHEMBL14527567 | 0.85 | FCER2 (0.52) | CAPN1FCER2CTSBMC1RMC4R | |
| SCHEMBL14527561 | 0.84 | BDKRB2 (0.49) | CAPN1MC1RMC4RMC3RPLG | |
| SCHEMBL14527564 | 0.84 | CAPN1 (0.51) | CAPN1FCER2CTSBMC1RMC4R | |
| SCHEMBL14527656 | 0.84 | PLG (0.53) | CAPN1FCER2CTSBMC1RMC4R | |
| SCHEMBL14527548 | 0.84 | CAPN1 (0.48) | CAPN1CTSBMC1RMC4RMC3R | |
| SCHEMBL14288708 | 0.84 | CAPN1 (0.48) | CAPN1CTSBMC1RMC4RMC3R | |
| SCHEMBL14527521 | 0.82 | CAPN1 (0.54) | CAPN1FCER2CTSBMC1RMC4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8138218-B2 | Growth hormone secretagogues | IPSEN PHARMA S.A.S. (FR) | 2012-03-20 | — | — | US | disclosed |
| US-20090131478-A1 | Growth Hormone Secretagogues | IPSEN PHARMA S.A.S. (FR) | 2009-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090131478-A1 | Growth Hormone Secretagogues | GHSR, GHRHR, GHITM | CAPN1 3316/4885FCER2 4722/4885CTSB 964/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.