Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 1/20 | 0.53 |
| ▸ | IMPDH2 | P12268 | 6/20 | 0.51 |
| ▸ | TGM2 | P21980 | 1/20 | 0.50 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.49 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.49 |
| ▸ | IMPDH1 | P20839 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | KRAS | P01116 | 5/20 | 0.46 |
| ▸ | HINT1 | P49773 | 1/20 | 0.46 |
| ▸ | FUT5 | Q11128 | 1/20 | 0.45 |
| ▸ | PNP | P00491 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29093004 | 0.83 | NT5E (0.56) | NT5EIMPDH2TGM2TAS1R3TAS1R1 | |
| SCHEMBL4409827 | 0.80 | NT5E (0.57) | NT5EIMPDH2TGM2TAS1R3TAS1R1 | |
| SCHEMBL18744141 | 0.79 | NT5E (0.51) | NT5EIMPDH2TGM2TAS1R3TAS1R1 | |
| SCHEMBL25388319 | 0.79 | NT5E (0.60) | NT5EIMPDH2TGM2TAS1R3TAS1R1 | |
| SCHEMBL12231345 | 0.78 | NT5E (0.53) | NT5EIMPDH2TGM2TAS1R3TAS1R1 | |
| SCHEMBL21636997 | 0.78 | NT5E (0.56) | NT5EIMPDH2TGM2TAS1R3TAS1R1 | |
| SCHEMBL21417496 | 0.78 | NT5E (0.56) | NT5EIMPDH2TGM2TAS1R3TAS1R1 | |
| SCHEMBL21636981 | 0.78 | NT5E (0.56) | NT5EIMPDH2TGM2TAS1R3TAS1R1 | |
| E626 SCHEMBL20677331 | 0.78 | NT5E (0.83) | NT5EIMPDH2TGM2TAS1R3TAS1R1 | |
| E626 SCHEMBL5854 | 0.78 | NT5E (0.83) | NT5EIMPDH2TGM2TAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022225827-A1 | NOVEL FORMS OF CYCLIC DINUCLEOTIDE COMPOUNDS | MERCK SHARP & DOHME LLC (US) | 2022-10-27 | — | — | WO | disclosed |
| WO-2022216577-A1 | NOVEL FORMS OF CYCLIC DINUCLEOTIDE COMPOUNDS | MERCK SHARP & DOHME LLC (US) | 2022-10-13 | — | — | WO | disclosed |