Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | PNMT | P11086 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | PDE2A | O00408 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23212814 | 1.00 | CES2 (0.41) | CES2CES1RIPK1GAAALDH1A1 | |
| SCHEMBL1396928 | 1.00 | CES2 (0.41) | CES2CES1RIPK1GAAALDH1A1 | |
| SCHEMBL20238836 | 0.84 | CES2 (0.48) | CES2CES1ALDH1A1HPGDCYP1A2 | |
| SCHEMBL28820045 | 0.84 | CYP1A2 (0.41) | ALDH1A1CYP1A2CYP3A4CYP2D6NFKB1 | |
| SCHEMBL22339022 | 0.84 | CES2 (0.48) | CES2CES1ALDH1A1HPGDCYP1A2 | |
| SCHEMBL23212908 | 0.84 | CYP1A2 (0.41) | ALDH1A1CYP1A2CYP3A4CYP2D6NFKB1 | |
| SCHEMBL2292937 | 0.84 | CYP1A2 (0.41) | ALDH1A1CYP1A2CYP3A4CYP2D6NFKB1 | |
| SCHEMBL1154723 | 0.84 | CES2 (0.48) | CES2CES1ALDH1A1HPGDCYP1A2 | |
| SCHEMBL16067539 | 0.84 | RIPK1 (0.39) | CES2CES1RIPK1GAAALDH1A1 | |
| SCHEMBL16055661 | 0.84 | RIPK1 (0.39) | CES2CES1RIPK1GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025096957-A1 | RAS-PI3K INHIBITORS AND USES THEREOF | VIVIDION THERAPEUTICS, INC. (US) | 2025-05-08 | — | — | WO | disclosed |
| CN-119823112-A | ATF6 modulators and uses thereof | 阿尔托斯实验室公司 | 2025-04-15 | — | — | CN | disclosed |
| CN-115135645-B | ATF6 modulators and uses thereof | 阿尔托斯实验室公司 | 2024-12-27 | — | — | CN | disclosed |
| CN-115135645-A | ATF6 modulators and uses thereof | 普拉西斯生物技术有限责任公司 | 2022-09-30 | — | — | CN | disclosed |