SCHEMBL29959709

SCHEMBL29959709

CC(C)(C)OC(=O)NCC1CCCOc2ccsc21

nearest known ligand 0.40

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ACACB O00763 8/20 0.36
ACACA Q13085 5/20 0.36
DRD2 P14416 2/20 0.36
EPHX1 P07099 1/20 0.34
HPGD P15428 2/20 0.34
KDM4E B2RXH2 1/20 0.34
LMNA P02545 1/20 0.34
GLA P06280 1/20 0.34
GAA P10253 1/20 0.34
MAPT P10636 1/20 0.34
CASP1 P29466 1/20 0.34
RAB9A P51151 1/20 0.34
CASP7 P55210 1/20 0.34
HSD17B10 Q99714 1/20 0.34
HTR4 Q13639 1/20 0.34
HCRTR2 O43614 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29960814 0.93 ACACB (0.39) ACACBACACADRD2HPGDKDM4E
Hydrochloric Acid SCHEMBL29960746 0.76 TAAR1 (0.44) DRD2
SCHEMBL29960757 0.75 ACACB (0.39) ACACBACACADRD2EPHX1HPGD
SCHEMBL29960238 0.72 DRD2 (0.39) ACACBACACADRD2KDM4E
SCHEMBL29960335 0.72 ACACB (0.44) ACACBACACADRD2
SCHEMBL29960785 0.72 P2RX7 (0.45) ACACBACACA
SCHEMBL14906835 0.72 DRD2 (0.42) ACACBACACADRD2EPHX1LMNA
SCHEMBL29960245 0.70 BRD4 (0.41) ACACBDRD2LMNA
SCHEMBL29960433 0.70 TAAR1 (0.41)
SCHEMBL17361826 0.69 KDM4C (0.51) ACACB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022204150-A1 COMPOUNDS AND COMPOSITIONS FOR TREATING CNS DISORDERS BLUE OAK PHARMACEUTICALS, INC. (US) 2022-09-29 WO disclosed