Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.37 |
| ▸ | ACACA | Q13085 | 3/20 | 0.35 |
| ▸ | CKS1B | P61024 | 1/20 | 0.34 |
| ▸ | SKP1 | P63208 | 1/20 | 0.34 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.34 |
| ▸ | KDM6B | O15054 | 2/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | NEK1 | Q96PY6 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29960814 | 0.81 | ACACB (0.39) | ACACBALDH1A1MAPTHPGDKDM4E | |
| SCHEMBL14906835 | 0.81 | DRD2 (0.42) | ACACBDRD2ACACACKS1BSKP1 | |
| SCHEMBL29960335 | 0.79 | ACACB (0.44) | ACACBDRD2ACACACKS1BSKP1 | |
| SCHEMBL29960403 | 0.78 | ACACB (0.38) | ACACBDRD2ACACACKS1BSKP1 | |
| SCHEMBL29960262 | 0.76 | GAA (0.44) | ACACBALDH1A1MAPTHPGDKDM4E | |
| SCHEMBL29959709 | 0.75 | ACACB (0.36) | ACACBMAPTHPGDKDM4EGLA | |
| SCHEMBL17361826 | 0.75 | KDM4C (0.51) | ACACBKDM6BKDM4C | |
| SCHEMBL29923119 | 0.75 | HTR1A (0.40) | ACACBDRD2ACACACKS1BSKP1 | |
| SCHEMBL17361953 | 0.75 | KDM4C (0.51) | ACACBKDM6BKDM4C | |
| SCHEMBL29923228 | 0.75 | HTR1A (0.40) | ACACBDRD2ACACACKS1BSKP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022204150-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CNS DISORDERS | BLUE OAK PHARMACEUTICALS, INC. (US) | 2022-09-29 | — | — | WO | disclosed |