Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 4/20 | 0.49 |
| ▸ | MAOB | P27338 | 4/20 | 0.48 |
| ▸ | MAOA | P21397 | 3/20 | 0.48 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | AHR | P35869 | 1/20 | 0.33 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11412674 | 0.78 | MAOB (0.50) | MAOBMAOAFTOALDH1A1HPGD | |
| SCHEMBL10504356 | 0.76 | MAOB (0.48) | ARMAOBMAOAFTOALDH1A1 | |
| SCHEMBL29568413 | 0.76 | MAOB (0.48) | MAOBMAOAFTOALDH1A1HPGD | |
| SCHEMBL30111795 | 0.76 | HTR2B (0.50) | ARMAOBMAOAFTOALDH1A1 | |
| SCHEMBL546446 | 0.76 | MAOB (0.48) | MAOBMAOAFTOALDH1A1HPGD | |
| SCHEMBL1857840 | 0.76 | HTR2B (0.50) | ARMAOBMAOAFTOALDH1A1 | |
| SCHEMBL28598875 | 0.74 | MAOB (0.38) | ARMAOBMAOAFTOKCNA3 | |
| SCHEMBL31107497 | 0.74 | MAOB (0.38) | ARMAOBMAOAFTOKCNA3 | |
| SCHEMBL28990321 | 0.72 | AR (0.41) | ARMAOBMAOAPARP1 | |
| SCHEMBL29959798 | 0.72 | MAOB (0.59) | ARMAOBMAOAFTOALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022204150-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CNS DISORDERS | BLUE OAK PHARMACEUTICALS, INC. (US) | 2022-09-29 | — | — | WO | disclosed |