Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.48 |
| ▸ | MAOA | P21397 | 3/20 | 0.48 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29568413 | 1.00 | MAOB (0.48) | MAOBMAOAFTOADORA2AELANE | |
| SCHEMBL11412674 | 0.78 | MAOB (0.50) | MAOBMAOAFTOKDM4ELMNA | |
| SCHEMBL29960477 | 0.76 | AR (0.49) | MAOBMAOAFTOKDM4ELMNA | |
| SCHEMBL10504356 | 0.76 | MAOB (0.48) | MAOBMAOAFTOKDM4ELMNA | |
| SCHEMBL30111795 | 0.76 | HTR2B (0.50) | MAOBMAOAFTOKDM4EATM | |
| SCHEMBL1857840 | 0.76 | HTR2B (0.50) | MAOBMAOAFTOKDM4EATM | |
| SCHEMBL1859617 | 0.76 | MAOB (0.59) | MAOBMAOAFTOKDM4ELMNA | |
| SCHEMBL29959798 | 0.76 | MAOB (0.59) | MAOBMAOAFTOKDM4ELMNA | |
| SCHEMBL20886870 | 0.72 | MAPT (0.53) | MAOAELANEKDM4ELMNAATM | |
| SCHEMBL30087046 | 0.72 | MAPT (0.53) | MAOAELANEKDM4ELMNAATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 89 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12195435-B2 | 5-methylchromone and the preparation method and application thereof | HAINAN MEDICAL UNIVERSITY (CN) | 2025-01-14 | — | — | US | claimed |
| CN-112174922-B | 5-methyl primary ketone and preparation method and application thereof | 海南医学院 | 2023-07-11 | — | — | CN | claimed |
| CN-113527244-B | 5-methyl chromone derivative and synthetic method and application thereof | 海南医学院 | 2023-02-03 | — | — | CN | claimed |
| US-20220324824-A1 | A 5-METHYLCHROMONE AND THE PREPARATION METHOD AND APPLICATION THEREOF | HAINAN MEDICAL UNIVERSITY (CN) | 2022-10-13 | — | — | US | claimed |
| CN-113527244-A | 5-methyl chromone derivative and synthetic method and application thereof | 海南医学院 | 2021-10-22 | — | — | CN | claimed |
| CN-112174922-A | 5-methyl chromone and preparation method and application thereof | 海南医学院 | 2021-01-05 | — | — | CN | claimed |
| US-12195435-B2 | 5-methylchromone and the preparation method and application thereof | HAINAN MEDICAL UNIVERSITY (CN) | 2025-01-14 | — | — | US | disclosed |
| US-12195435-B2 | 5-methylchromone and the preparation method and application thereof | HAINAN MEDICAL UNIVERSITY (CN) | 2025-01-14 | — | — | US | disclosed |
| US-12195435-B2 | 5-methylchromone and the preparation method and application thereof | HAINAN MEDICAL UNIVERSITY (CN) | 2025-01-14 | — | — | US | disclosed |
| CN-117777119-A | Method for extracting and purifying aloesin from aloe product | 高陵蓝晓科技新材料有限公司 | 2024-03-29 | — | — | CN | disclosed |
| US-11857657-B2 | Diarylalkanes as potent inhibitors of binuclear enzymes | UNIGEN, INC. (US) | 2024-01-02 | — | — | US | disclosed |
| CN-112174922-B | 5-methyl primary ketone and preparation method and application thereof | 海南医学院 | 2023-07-11 | — | — | CN | disclosed |
| US-20230142062-A1 | THE APPLICATION OF ALOESIN IN THE PREPARATION OF PRODUCTS FOR PREVENTING OR TREATING OBESITY | HAINAN MEDICAL UNIVERSITY (CN) | 2023-05-11 | — | — | US | disclosed |
| WO-1998052934-A1 | METHOD FOR THE SYNTHESIS OF 8-C-β-D-[2'-O-(E)-CINNAMOYL] GLYCOPYRANOSYL-2-[2-HYDROXY] PROPYL-7-METHOXY-5-METHYLCHROMONE | UNIVERA PHARMACEUTICALS, INC. (US) | 1998-11-26 | — | — | WO | disclosed |
| US-5801256-A | Method for the synthesis of 8-C-β-D 2'-O-(E)-cinnamoyl!glycopyranosyl-2- 2-hydroxy!propyl-7-methoxy-5-methylchromone | UNIVERA PHARMACEUTICALS, INC. (US) | 1998-09-01 | — | — | US | disclosed |
| US-5801256-A | Method for the synthesis of 8-C-β-D 2'-O-(E)-cinnamoyl!glycopyranosyl-2- 2-hydroxy!propyl-7-methoxy-5-methylchromone | UNIVERA PHARMACEUTICALS, INC. (US) | 1998-09-01 | — | — | US | disclosed |
| EP-0817636-A4 | CINNAMOYL-C-GLYCOSIDE CHROMONE ISOLATED FROM ALOE BARBADENSIS | UNIVERA PHARM INC (US) | 1998-05-06 | — | — | EP | disclosed |
| EP-0817636-A1 | CINNAMOYL-C-GLYCOSIDE CHROMONE ISOLATED FROM ALOE BARBADENSIS | Univera Pharmaceuticals, Inc. (US) | 1998-01-14 | — | — | EP | disclosed |
| WO-1996040182-A1 | IDENTIFICATION OF A POTENT ANTIOXIDANT FROM ALOE BARBADENSIS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1996-12-19 | — | — | WO | disclosed |
| WO-1996025937-A1 | CINNAMOYL-C-GLYCOSIDE CHROMONE ISOLATED FROM ALOE BARBADENSIS | UNIVERA PHARMACEUTICALS, INC. (US) | 1996-08-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12195435-B2 | 5-methylchromone and the preparation method and application thereof | TYR, DHCR7, CYP46A1 | MAOB 22/4885MAOA 26/4885FTO 74/4885 |
| US-20220324824-A1 | A 5-METHYLCHROMONE AND THE PREPARATION METHOD AND APPLICATION THEREOF | TYR, DHCR7, CYP51A1 | MAOB 24/4885MAOA 23/4885FTO 70/4885 |
| US-11857657-B2 | Diarylalkanes as potent inhibitors of binuclear enzymes | TYR, DDT, HAAO | MAOB 18/4885MAOA 7/4885FTO 1197/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.