Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | HPGD | P15428 | 4/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 6/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.56 |
| ▸ | MAOA | P21397 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.53 |
| ▸ | AR | P10275 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1859617 | 1.00 | MAOB (0.59) | MAOBALDH1A1HPGDKDM4ELMNA | |
| SCHEMBL3843389 | 0.78 | HDAC4 (0.51) | MAOBALDH1A1HPGDKDM4ELMNA | |
| SCHEMBL1472177 | 0.76 | KDM4E (0.57) | ALDH1A1HPGDKDM4ELMNASMN1; SMN2 | |
| SCHEMBL10517239 | 0.76 | MAOB (0.63) | MAOBALDH1A1HPGDKDM4ELMNA | |
| SCHEMBL27746734 | 0.76 | MAOB (0.63) | MAOBALDH1A1HPGDKDM4ELMNA | |
| SCHEMBL11655753 | 0.76 | MAOB (0.59) | MAOBALDH1A1HPGDKDM4ELMNA | |
| SCHEMBL29568413 | 0.76 | MAOB (0.48) | MAOBALDH1A1HPGDKDM4ELMNA | |
| SCHEMBL546446 | 0.76 | MAOB (0.48) | MAOBALDH1A1HPGDKDM4ELMNA | |
| SCHEMBL17237767 | 0.74 | ABCB1 (0.53) | ALDH1A1HPGDKDM4ESMN1; SMN2NPC1 | |
| SCHEMBL9976085 | 0.74 | ALDH1A1 (0.65) | ALDH1A1HPGDKDM4ELMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4511018-A1 | 4-CHROMONE DERIVATIVES AS N-POLYMERASE INHIBITORS FOR USE IN THE TREATMENT PLATINUM RESISTANT METASTATIC NEOPLASM | Fondazione Istituto Italiano di Tecnologia (IT) | 2025-02-26 | — | — | EP | disclosed |
| WO-2023203535-A1 | 4-CHROMONE DERIVATIVES AS N-POLYMERASE INHIBITORS FOR USE IN THE TREATMENT PLATINUM RESISTANT METASTATIC NEOPLASM | FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA (IT) | 2023-10-26 | — | — | WO | disclosed |
| EP-4103164-A1 | COMPOUNDS FOR TREATING CORONAVIRUS INFECTION | NLC Pharma Ltd (IL) | 2022-12-21 | — | — | EP | disclosed |
| WO-2022204150-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CNS DISORDERS | BLUE OAK PHARMACEUTICALS, INC. (US) | 2022-09-29 | — | — | WO | disclosed |