Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 11/20 | 0.50 |
| ▸ | USP30 | Q70CQ3 | 4/20 | 0.48 |
| ▸ | JAK2 | O60674 | 1/20 | 0.46 |
| ▸ | JAK1 | P23458 | 1/20 | 0.46 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29960446 | 0.83 | GPR119 (0.48) | GPR119USP30JAK2JAK1KDM4E | |
| SCHEMBL29960559 | 0.81 | DRD2 (0.47) | GPR119USP30JAK2JAK1KDM4E | |
| SCHEMBL29960219 | 0.81 | DRD2 (0.47) | GPR119USP30JAK2JAK1KDM4E | |
| SCHEMBL2227245 | 0.78 | GPR119 (0.47) | GPR119USP30JAK2JAK1PTPN2 | |
| SCHEMBL6422733 | 0.77 | GPR119 (0.46) | GPR119USP30KDM4EPKM | |
| SCHEMBL15259715 | 0.76 | USP30 (0.45) | GPR119USP30 | |
| SCHEMBL7712465 | 0.76 | GPR119 (0.56) | GPR119JAK2JAK1PTPN2PTPN1 | |
| SCHEMBL5636127 | 0.76 | HTR2A (0.45) | GPR119USP30JAK2JAK1 | |
| SCHEMBL860735 | 0.74 | DRD2 (0.43) | — | |
| SCHEMBL860734 | 0.74 | DRD2 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022204150-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CNS DISORDERS | BLUE OAK PHARMACEUTICALS, INC. (US) | 2022-09-29 | — | — | WO | disclosed |