Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.49 |
| ▸ | AKT1 | P31749 | 1/20 | 0.45 |
| ▸ | CNKSR1 | Q969H4 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15888927 | 0.90 | KEAP1 (0.47) | HSD17B10TSHRKDM4EMAPTLMNA | |
| SCHEMBL10783189 | 0.81 | CA12 (0.59) | KDM4EMAPTLMNAMDM2CA12 | |
| SCHEMBL8740665 | 0.81 | MAPT (0.55) | TSHRKDM4EMAPTLMNAMDM2 | |
| SCHEMBL4796094 | 0.81 | MAPT (0.51) | KDM4EMAPTLMNAMDM2CA12 | |
| SCHEMBL1405343 | 0.80 | LMNA (0.53) | HSD17B10TSHRKDM4EMAPTLMNA | |
| SCHEMBL1405342 | 0.80 | LMNA (0.53) | HSD17B10TSHRKDM4EMAPTLMNA | |
| SCHEMBL11054639 | 0.79 | CA12 (0.57) | KDM4EMAPTLMNAMDM2CA12 | |
| SCHEMBL28970711 | 0.77 | MAPT (0.51) | KDM4EMAPTLMNAMDM2CA12 | |
| SCHEMBL1897277 | 0.76 | CA12 (0.54) | KDM4EMAPTLMNAMDM2CA12 | |
| SCHEMBL1897276 | 0.76 | CA12 (0.54) | KDM4EMAPTLMNAMDM2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022204150-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CNS DISORDERS | BLUE OAK PHARMACEUTICALS, INC. (US) | 2022-09-29 | — | — | WO | disclosed |