SCHEMBL29960744

SCHEMBL29960744

O=[N+]([O-])CC1CCOc2cccc(Cl)c21

nearest known ligand 0.37

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MAP3K14 Q99558 2/20 0.37
P2RY6 Q15077 2/20 0.33
CA2 P00918 1/20 0.32
FABP4 P15090 1/20 0.31
MAPT P10636 1/20 0.31
MAPK1 P28482 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
KDM6B O15054 2/20 0.31
KDM4C Q9H3R0 2/20 0.31
HSP90AA1 P07900 1/20 0.30
OPRL1 P41146 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL29960492 0.77 MAP3K14 (0.41) MAP3K14CA2OPRL1
SCHEMBL136087 0.71 MAP3K14 (0.46) MAP3K14CA2L3MBTL1OPRL1
SCHEMBL29960339 0.70
SCHEMBL29960441 0.70
SCHEMBL19829902 0.69 MAP3K14 (0.45) MAP3K14CA2OPRL1
SCHEMBL29960294 0.69
SCHEMBL9015271 0.68 MAP3K14 (0.35) MAP3K14OPRL1
SCHEMBL1804999 0.67 ADRA2A (0.38) P2RY6
SCHEMBL31607014 0.64 PSMB5 (0.42)
SCHEMBL29960243 0.63

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022204150-A1 COMPOUNDS AND COMPOSITIONS FOR TREATING CNS DISORDERS BLUE OAK PHARMACEUTICALS, INC. (US) 2022-09-29 WO disclosed