SCHEMBL29961908

SCHEMBL29961908

Oc1cccc2ccc3c(c12)Cc1ccccc1-3

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PNMT P11086 1/20 0.47
TSHR P16473 2/20 0.42
CYP3A4 P08684 1/20 0.42
HTR7 P34969 2/20 0.42
HTR2B P41595 2/20 0.42
NPC1 O15118 3/20 0.42
RAB9A P51151 3/20 0.42
ALDH1A1 P00352 5/20 0.40
KDM4E B2RXH2 3/20 0.40
HPGD P15428 2/20 0.40
CDK4 P11802 1/20 0.38
CCND1 P24385 1/20 0.38
DRD2 P14416 3/20 0.37
DRD3 P35462 2/20 0.37
DRD1 P21728 1/20 0.37
DRD5 P21918 1/20 0.37
ADRA1D P25100 1/20 0.37
HTR2A P28223 1/20 0.37
HTR2C P28335 1/20 0.37
ADRA1A P35348 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5999294 1.00 PNMT (0.47) PNMTTSHRCYP3A4HTR7HTR2B
Acetonitrile SCHEMBL28758116 0.91 PNMT (0.41) PNMTTSHRCYP3A4HTR7HTR2B
SCHEMBL30015218 0.80 PNMT (0.47) PNMTTSHRCYP3A4HTR7HTR2B
SCHEMBL10946081 0.80 PNMT (0.44) PNMTTSHRCYP3A4HTR7HTR2B
SCHEMBL10685341 0.80 PNMT (0.47) PNMTTSHRCYP3A4HTR7HTR2B
SCHEMBL28066886 0.80 PNMT (0.58) PNMTTSHRCYP3A4HTR7HTR2B
SCHEMBL58474 0.80 PNMT (0.58) PNMTTSHRCYP3A4HTR7HTR2B
SCHEMBL9123572 0.80 HTR2B (0.46) PNMTTSHRCYP3A4HTR7HTR2B
SCHEMBL4855313 0.79 CA1 (0.42) PNMTTSHRCYP3A4HTR7HTR2B
Hydrochloric Acid SCHEMBL29546213 0.79 PNMT (0.42) PNMTTSHRCYP3A4HTR7HTR2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110636884-B Novel crystalline forms 吉利德科学公司 2022-10-04 CN disclosed