SCHEMBL58474

SCHEMBL58474

Oc1cccc2c1Cc1ccccc1-2

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PNMT P11086 1/20 0.58
NPC1 O15118 3/20 0.50
RAB9A P51151 3/20 0.50
DRD2 P14416 3/20 0.49
DRD3 P35462 3/20 0.49
DRD1 P21728 1/20 0.49
DRD5 P21918 1/20 0.49
CA1 P00915 3/20 0.47
CA2 P00918 3/20 0.47
CA4 P22748 3/20 0.47
CA6 P23280 3/20 0.47
BCL2L1 Q07817 1/20 0.47
BAD Q92934 1/20 0.47
HTR7 P34969 1/20 0.46
HTR2B P41595 1/20 0.46
MIF P14174 2/20 0.42
MAOA P21397 1/20 0.41
DRD4 P21917 1/20 0.41
ALDH1A1 P00352 3/20 0.41
MAPT P10636 3/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dimethylamine SCHEMBL15440644 0.92 NPC1 (0.53) PNMTNPC1RAB9ADRD2DRD3
Phenol SCHEMBL29142512 0.92 PNMT (0.51) PNMTNPC1RAB9ADRD2DRD3
SCHEMBL382855 0.89 PNMT (0.56) PNMTNPC1RAB9ADRD2DRD3
SCHEMBL2465337 0.86 PNMT (0.53) PNMTNPC1RAB9ADRD2DRD3
SCHEMBL11607235 0.84 MAOA (0.61) NPC1RAB9AMIFMAOAALDH1A1
SCHEMBL30103334 0.84 PNMT (0.63) PNMTNPC1RAB9ADRD2DRD3
SCHEMBL524602 0.84 PNMT (0.63) PNMTNPC1RAB9ADRD2DRD3
SCHEMBL29034014 0.84 CA2 (0.55) NPC1RAB9ADRD2DRD3DRD1
SCHEMBL2877998 0.81 PNMT (0.61) PNMTNPC1RAB9ADRD2DRD3
Fluorene SCHEMBL28466769 0.81 MAOA (0.54) PNMTNPC1RAB9ACA2CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 998 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117362644-B Polyimide resin for improving hydrophobicity of cotton fabric and preparation method thereof 韶关市北纺智造科技有限公司 2024-09-03 CN claimed
CN-113861068-B Molecular probe for related-on-off-on conversion signals of acid and alkali and application thereof 德州学院 2024-01-16 CN claimed
CN-117362644-A Polyimide resin for improving hydrophobicity of cotton fabric and preparation method thereof 韶关市北纺智造科技有限公司 2024-01-09 CN claimed
CN-107963972-B Organic electroluminescent device 保土谷化学工业株式会社 2021-09-03 CN claimed
US-10745372-B2 Compound, resin, material for forming underlayer film for lithography, underlayer film for lithography, pattern forming method, and purification method MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2020-08-18 US claimed
WO-2020143265-A1 FLUORIDE ION COLOR-SENSING POLYIMIDE FILM, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF 华南理工大学 2020-07-16 WO claimed
CN-111377847-A Heterocyclic compound, composition comprising the same, and organic light-emitting device comprising the heterocyclic compound 三星电子株式会社 2020-07-07 CN claimed
CN-109796613-B Fluorine ion color development sensing polyimide film and preparation method and application thereof 华南理工大学 2020-05-22 CN claimed
US-10326081-B2 Organic light-emitting device having improved efficiency characteristics and organic light-emitting display apparatus including the same SAMSUNG DISPLAY CO., LTD. (KR) 2019-06-18 US claimed
EP-3312224-B1 POLYAMIDE MOULDING COMPOSITION AND MULTI-LAYERED STRUCTURE MADE HEREFROM EMS PATENT AG (CH) 2018-12-26 EP claimed
US-20100081776-A1 TRANSITION METAL CATALYTIC SYSTEMS AND METHODS FOR PREPARING ETHYLENE HOMOPOLYMERS OR COPOLYMERS OF ETHYLENE AND a-OLEFINS USING THE SAME SABIC SK NEXLENE COMPANY PTE. LTD. (SG) 2010-04-01 US claimed
WO-2010036025-A2 TRANSITION METAL CATALYTIC SYSTEMS AND METHODS FOR PREPARING ETHYLENE HOMOPOLYMERS OR COPOLYMERS OF ETHYLENE AND α- OLEFINS USING THE SAME. SK ENERGY CO., LTD. (KR) 2010-04-01 WO claimed
US-20100009197-A1 POWDER COATING FLUOROPOLYMER COMPOSITIONS CONTAINING MONO-HYDROXY AROMATIC MATERIALS 3M INNOVATIVE PROPERTIES COMPANY (US) 2010-01-14 US claimed
EP-2076566-A2 POWDER COATING FLUOROPOLYMER COMPOSITIONS CONTAINING MONO-HYDROXY AROMATIC MATERIALS 3M Innovative Properties Company (US) 2009-07-08 EP claimed
WO-2008048884-A2 POWDER COATING FLUOROPOLYMER COMPOSITIONS CONTAINING MONO-HYDROXY AROMATIC MATERIALS 3M INNOVATIVE PROPERTIES COMPANY (US) 2008-04-24 WO claimed
US-20070197524-A1 Fluorenes and carbazoles as ligands of the EP2 receptor BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) 2007-08-23 US claimed
US-20070117215-A1 Room temperature phosphorescence apparatus and methods POLYMER CONCEPTS TECHNOLOGIES PBY, INC. 2007-05-24 US claimed
US-5776932-A ANTIALLERGENS, ANTIASTHMATICS, ANTIINFLAMMATORY AGENTS AND MODULATORS ARZNEIMITTELWERK DRESDEN G.M.B.H. (DE) 1998-07-07 US claimed
EP-0113293-B1 LIQUID CRYSTALS FAMILY WITH A SMECTIC A PHASE, AND PROCESS FOR ITS PREPARATION THOMSON-CSF (FR) 1986-08-20 EP claimed
EP-0113293-A1 Liquid crystals family with a smectic A phase, and process for its preparation THOMSON-CSF (FR) 1984-07-11 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100081776-A1 TRANSITION METAL CATALYTIC SYSTEMS AND METHODS FOR PREPARING ETHYLENE HOMOPOLYMERS OR COPOLYMERS OF ETHYLENE AND a-OLEFINS USING THE SAME ESR1, AOC3, PPOX PNMT 502/4885NPC1 2801/4885RAB9A 3609/4885
US-20070197524-A1 Fluorenes and carbazoles as ligands of the EP2 receptor PTGER2, PTGER1, PTGDR2 PNMT 753/4885NPC1 1301/4885RAB9A 2665/4885
US-10745372-B2 Compound, resin, material for forming underlayer film for lithography, underlayer film for lithography, pattern forming method, and purification method ASH2L, MLLT1, FRG1 PNMT 2632/4885NPC1 943/4885RAB9A 2864/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.