Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.32 |
| ▸ | EP300 | Q09472 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5233014 | 0.90 | SCN9A (0.40) | SCN9ACYP3A4CYP2C19CYP2D6CYP2C9 | |
| SCHEMBL2996276 | 0.82 | ALDH1A1 (0.35) | KDM4ETSHRHSD17B10 | |
| SCHEMBL2157499 | 0.81 | KDM4E (0.34) | CYP2C19KDM4ETSHRHSD17B10 | |
| SCHEMBL2998707 | 0.81 | KDM4E (0.36) | KDM4E | |
| SCHEMBL2157328 | 0.80 | KDM4E (0.31) | CYP2D6KDM4ETSHRHSD17B10 | |
| SCHEMBL2988625 | 0.80 | PTGDR (0.35) | — | |
| SCHEMBL2156720 | 0.79 | KDM4E (0.37) | KDM4ETSHRHSD17B10 | |
| SCHEMBL1173457 | 0.78 | SCN9A (0.51) | SCN9ACYP3A4CYP2C19CYP2D6CYP2C9 | |
| SCHEMBL2994234 | 0.78 | SCN9A (0.38) | SCN9ACYP3A4CYP2C19CYP2D6CYP2C9 | |
| SCHEMBL10293481 | 0.77 | SCN9A (0.54) | SCN9ACYP3A4CYP2C19CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7781431-B2 | Thienopyrroles as antiviral agents | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P ANGELETTI SPA (IT) | 2010-08-24 | — | — | US | disclosed |
| US-20090036443-A1 | Thienopyrroles as antiviral agents | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI (IT) | 2009-02-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090036443-A1 | Thienopyrroles as antiviral agents | ZC3HAV1, XDH, TPMT | SCN9A 3612/4885CYP3A4 72/4885CYP2C19 154/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.