Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | GRM6 | O15303 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5233022 | 0.90 | KDM4E (0.38) | ALDH1A1LMNAKDM4ESMN1; SMN2KMT2A | |
| SCHEMBL2998711 | 0.83 | ALDH1A1 (0.42) | ALDH1A1LMNAKDM4ESMN1; SMN2KMT2A | |
| SCHEMBL2996273 | 0.82 | SCN9A (0.38) | KDM4EHSD17B10TSHR | |
| SCHEMBL2157504 | 0.82 | KDM4E (0.39) | ALDH1A1LMNAKDM4ESMN1; SMN2KMT2A | |
| SCHEMBL2157334 | 0.81 | ALDH1A1 (0.35) | ALDH1A1LMNAKDM4ESMN1; SMN2KMT2A | |
| SCHEMBL2988628 | 0.78 | KDM4E (0.38) | ALDH1A1LMNAKDM4ESMN1; SMN2KMT2A | |
| SCHEMBL2156729 | 0.78 | MAPT (0.39) | ALDH1A1LMNAKDM4EKMT2AHSD17B10 | |
| SCHEMBL2994236 | 0.76 | GRIN2B (0.35) | ALDH1A1LMNA | |
| SCHEMBL2994395 | 0.75 | KDM4E (0.47) | ALDH1A1LMNAKDM4ESMN1; SMN2KMT2A | |
| SCHEMBL2156914 | 0.74 | ALDH1A1 (0.39) | ALDH1A1LMNAKDM4ESMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7781431-B2 | Thienopyrroles as antiviral agents | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P ANGELETTI SPA (IT) | 2010-08-24 | — | — | US | disclosed |
| US-20090036443-A1 | Thienopyrroles as antiviral agents | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI (IT) | 2009-02-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090036443-A1 | Thienopyrroles as antiviral agents | ZC3HAV1, XDH, TPMT | ALDH1A1 397/4885LMNA 3405/4885KDM4E 3250/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.