Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 15/20 | 0.72 |
| ▸ | BCHE | P06276 | 17/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL131315 | 0.98 | ACHE (0.69) | BCHEACHE | |
| Hydrochloric Acid SCHEMBL1099708 | 0.96 | ACHE (0.72) | BCHEACHE | |
| Iodide SCHEMBL3434198 | 0.96 | ACHE (0.67) | BCHEACHE | |
| SCHEMBL4389303 | 0.91 | ACHE (0.61) | BCHEACHE | |
| SCHEMBL29657227 | 0.91 | ACHE (0.61) | BCHEACHE | |
| Bromide SCHEMBL10988989 | 0.76 | BCHE (0.44) | BCHEACHE | |
| SCHEMBL10615714 | 0.76 | ACHE (0.76) | BCHEACHE | |
| SCHEMBL25613361 | 0.74 | BCHE (0.83) | BCHEACHE | |
| Bromide SCHEMBL14937532 | 0.72 | BCHE (1.00) | BCHEACHE | |
| Bromide SCHEMBL4890409 | 0.72 | BCHE (1.00) | BCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 492 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210093724-A1 | TOPICAL ANTI-ACNE COMPOSITION | CONCEPT MATRIX SOLUTIONS | 2021-04-01 | — | — | US | claimed |
| WO-2016010984-A2 | COMPOSITIONS AND METHODS FOR TREATING ROSACEA | TISSUE TECH, INC. (US) | 2016-01-21 | — | — | WO | claimed |
| US-20160008295-A1 | COMPOSITIONS AND METHODS FOR TREATING ROSACEA | TISSUE TECH, INC. | 2016-01-14 | — | — | US | claimed |
| US-20140154342-A1 | SANDALWOOD OIL AND ITS USES RELATED TO SKIN DISORDERS | SANTALIS PHARMACEUTICALS INC. (US) | 2014-06-05 | — | — | US | claimed |
| EP-2736504-A1 | SANDALWOOD OIL AND ITS USES RELATED TO SKIN DISORDERS | Santalis Pharmaceuticals Inc. (US) | 2014-06-04 | — | — | EP | claimed |
| US-20130203969-A1 | USE OF SMALL MOLECULES IN METHODS FOR PURIFICATION OF BIOMOLECULES | EMD MILLIPORE CORPORATION (US) | 2013-08-08 | — | — | US | claimed |
| WO-2013016656-A1 | SANDALWOOD OIL AND ITS USES RELATED TO SKIN DISORDERS | SANTALIS PHARMACEUTICALS INC. (US) | 2013-01-31 | — | — | WO | claimed |
| US-5830488-A | QUICK-DRYING; ALCOHOL, CATIONIC DISINFECTANT AND SILICONE | SHISEIDO CO., LTD. (JP) | 1998-11-03 | — | — | US | claimed |
| WO-1997000609-A1 | METHOD FOR INCREASING THE EFFICACY OF AN ODOR MASKING AGENT | HENKEL CORPORATION (US) | 1997-01-09 | — | — | WO | claimed |
| US-5089252-A | Amphoteric polymer of betainised dialkylaminoalkyl acrylate or dialkylaminoalkyl acrylamide and cationic deriative | L'OREAL (FR) | 1992-02-18 | — | — | US | claimed |
| JP-56030902-A | — | — | None | — | — | JP | disclosed |
| CN-118159133-A | Permanent disinfection composition and method for permanent disinfection | 法国特种经营公司 | 2024-06-07 | — | — | CN | disclosed |
| WO-2024092394-A1 | ANTIMICROBIAL FOAM HAND SOAP COMPOSITIONS WITH COLOR INDICATOR SYSTEMS | ECOLAB USA INC. (US) | 2024-05-10 | — | — | WO | disclosed |
| WO-2024085105-A1 | ANTI-INFLAMMATORY AGENT, TNF-α PRODUCTION INHIBITOR, INTERLEUKIN-10 PRODUCTION PROMOTOR, SKIN EXTERNAL APPLICATION COMPOSITION, FOOD OR BEVERAGE COMPOSITION, METHOD FOR PREVENTING, AMELIORATING, OR TREATING INFLAMMATORY DISEASES, AND USE OF PLANT-DERIVED POLYAMINE-CONTAINING EXTRACT FOR MANUFACTURING ANTI-INFLAMMATORY AGENT | 東洋紡株式会社 | 2024-04-25 | — | — | WO | disclosed |
| US-11964042-B2 | Additive for medicinal agents | NIPPON SHOKUBAI CO., LTD. (JP) | 2024-04-23 | — | — | US | disclosed |
| US-4163038-A | ACTIVE INGREDIENT AND BLOWING AGENT | EARTH CHEMICAL COMPANY, LIMITED (JP) | 1979-07-31 | — | — | US | disclosed |
| US-4051234-A | BIS-GUANIDINE COMPOUND, ETHYLENEDIAMINEDIACETIC ACID OR SALT AS CHELATOR | THE PROCTER & GAMBLE COMPANY (US) | 1977-09-27 | — | — | US | disclosed |
| US-4025616-A | Oral compositions for plaque, caries and calculus retardation with reduced staining tendencies | THE PROCTER & GAMBLE COMPANY (US) | 1977-05-24 | — | — | US | disclosed |
| US-3937807-A | BISBIGUANIDE COMPOUND | THE PROCTER & GAMBLE COMPANY (US) | 1976-02-10 | — | — | US | disclosed |
| US-3934002-A | BIS-GUANIDE | THE PROCTER & GAMBLE COMPANY (US) | 1976-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210093724-A1 | TOPICAL ANTI-ACNE COMPOSITION | CUTA, EBP, CNR2 | ACHE 3814/4885BCHE 3481/4885 |
| US-11964042-B2 | Additive for medicinal agents | ADM2, NQO1, MRPL21 | ACHE 508/4885BCHE 1848/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.