Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 14/20 | 0.72 |
| ▸ | BCHE | P06276 | 13/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL131315 | 0.98 | ACHE (0.69) | ACHEBCHE | |
| Bromide SCHEMBL299633 | 0.96 | BCHE (0.72) | ACHEBCHE | |
| Iodide SCHEMBL3434198 | 0.96 | ACHE (0.67) | ACHEBCHE | |
| SCHEMBL29657227 | 0.91 | ACHE (0.61) | ACHEBCHE | |
| SCHEMBL4389303 | 0.91 | ACHE (0.61) | ACHEBCHE | |
| SCHEMBL10615714 | 0.76 | ACHE (0.76) | ACHEBCHE | |
| SCHEMBL25613361 | 0.74 | BCHE (0.83) | ACHEBCHE | |
| Bromide SCHEMBL10988989 | 0.73 | BCHE (0.44) | ACHEBCHE | |
| Hedaquinium SCHEMBL2733777 | 0.72 | BCHE (0.96) | ACHEBCHE | |
| SCHEMBL1128053 | 0.71 | ACHE (0.63) | ACHEBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 94 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5089252-A | Amphoteric polymer of betainised dialkylaminoalkyl acrylate or dialkylaminoalkyl acrylamide and cationic deriative | L'OREAL (FR) | 1992-02-18 | — | — | US | claimed |
| US-11825842-B2 | Quaternary amine formulations and uses thereof | AURORIUM HOLDINGS LLC (US) | 2023-11-28 | — | — | US | disclosed |
| WO-2023164152-A1 | MULTI-MODAL HAIR CARE COMPOSITION COMPRISING CATIONIC GUAR BLENDS AND PROCESS FOR PREPARATION THEREOF | ISP INVESTMENTS LLC (US) | 2023-08-31 | — | — | WO | disclosed |
| EP-3965722-B1 | TOPICAL COMPOSITIONS WITH PRESERVATIVE SYSTEM | DSM IP ASSETS BV (NL) | 2023-08-16 | — | — | EP | disclosed |
| EP-3965721-B1 | TOPICAL COMPOSITIONS WITH ANTIMICROBIAL AGENT MIXTURE | DSM IP ASSETS BV (NL) | 2023-06-14 | — | — | EP | disclosed |
| US-20220211594-A1 | TOPICAL COMPOSITIONS | DSM IP ASSETS B.V. (NL) | 2022-07-07 | — | — | US | disclosed |
| US-11364208-B2 | Topical compositions | DSM IP ASSETS B.V. (NL) | 2022-06-21 | — | — | US | disclosed |
| US-11324680-B2 | Topical compositions | DSM IP ASSETS B.V. (NL) | 2022-05-10 | — | — | US | disclosed |
| US-11306054-B2 | Propanediol monoacetate mononitrate | DSM IP ASSETS B.V. (NL) | 2022-04-19 | — | — | US | disclosed |
| US-11248345-B2 | Dissolved air de-bonding of a tissue sheet | GPCP IP HOLDINGS LLC (US) | 2022-02-15 | — | — | US | disclosed |
| US-20020010112-A1 | Aqueous or aqueous-alcoholic body cleansing compositions comprising sorbitol esters | CLARIANT GMBH | 2002-01-24 | — | — | US | disclosed |
| US-20020006882-A1 | Aqueous or aqueous-alcoholic body-cleansing compositions comprising oligoesters | CLARIANT GMBH | 2002-01-17 | — | — | US | disclosed |
| US-5148822-A | Applying a quaternary ammonium compound having an alkyl group attached to the ammonium nitrogen of nonprotein or protein material | JOHNSON PRODUCTS CO., INC. (US) | 1992-09-22 | — | — | US | disclosed |
| US-5139037-A | Amphoteric polymer of betanized dialkylaminoalkyl (meth)acrylate or (meth)acrylamide and a cationic polymer | L'OREAL (FR) | 1992-08-18 | — | — | US | disclosed |
| US-5089252-A | Amphoteric polymer of betainised dialkylaminoalkyl acrylate or dialkylaminoalkyl acrylamide and cationic deriative | L'OREAL (FR) | 1992-02-18 | — | — | US | disclosed |
| US-5060680-A | Applying alkaline straightener, rinsing, applying aqueous alkaline composition containing quaternary ammonium salt | JOHNSON PRODUCTS CO., INC. (US) | 1991-10-29 | — | — | US | disclosed |
| WO-1989002233-A1 | HAIR STRAIGHTENING METHOD AND TEXTURING STRENGTHENER COMPOSITION | JOHNSON PRODUCTS CO., INC. (US) | 1989-03-23 | — | — | WO | disclosed |
| US-4638822-A | CATIONIC AND ANIONIC POLYMERS | L'OREAL (FR) | 1987-01-27 | — | — | US | disclosed |
| US-RE31126-E | Quaternary ammonium compounds in pretreatment of hair before shampooing with an anionic shampoo | ALBERTO-CULVER COMPANY (US) | 1983-01-18 | — | — | US | disclosed |
| US-4061150-A | Quaternary ammonium compounds in pretreatment of hair before shampooing with an anionic shampoo | ALBERTO-CULVER COMPANY (US) | 1977-12-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020006882-A1 | Aqueous or aqueous-alcoholic body-cleansing compositions comprising oligoesters | ADH1C, ADH1A, ADH5 | ACHE 2823/4885BCHE 611/4885 |
| US-11306054-B2 | Propanediol monoacetate mononitrate | DERA, PHGDH, PGD | ACHE 2371/4885BCHE 2167/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.