Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 2/20 | 0.45 |
| ▸ | GABRD | O14764 | 2/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.45 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.45 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.45 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.45 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.45 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.45 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.45 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.45 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.45 |
| ▸ | GABRE | P78334 | 2/20 | 0.45 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.45 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.45 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.45 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | FAAH | O00519 | 4/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29963921 | 1.00 | GABRP (0.45) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL12329360 | 0.85 | FFAR4 (0.49) | FAAHCNR1CNR2 | |
| SCHEMBL16050707 | 0.82 | TSHR (0.46) | FAAHCNR1CNR2SLC1A1 | |
| SCHEMBL1743788 | 0.82 | GABRP (0.43) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL880131 | 0.80 | FAAH (0.44) | FAAHCNR1CNR2HDAC1HDAC2 | |
| SCHEMBL30547117 | 0.80 | FAAH (0.44) | FAAHCNR1CNR2HDAC1HDAC2 | |
| SCHEMBL28745724 | 0.80 | L3MBTL1 (0.46) | CYP1A2FAAHCNR1CNR2 | |
| SCHEMBL9508041 | 0.79 | GABRR1 (0.45) | CYP1A2FAAHCNR1CNR2HDAC1 | |
| SCHEMBL10550854 | 0.78 | FAAH (0.40) | FAAHCNR1CNR2 | |
| SCHEMBL1711788 | 0.78 | TSHR (0.48) | GABRPGABRDGABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4092127-A1 | ENZYME-CATALYTIC METHOD FOR THE DIRECT STEREOSELECTIVE SYNTHESIS OF GAMMA-(ACYLOXY) CARBOXYLIC ACIDS | Tallinn University of Technology (EE) | 2022-11-23 | — | — | EP | disclosed |