Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 4/20 | 0.50 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.50 |
| ▸ | MMP2 | P08253 | 3/20 | 0.43 |
| ▸ | MMP9 | P14780 | 3/20 | 0.43 |
| ▸ | MMP12 | P39900 | 2/20 | 0.43 |
| ▸ | FPR2 | P25090 | 1/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.42 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.42 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.42 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.42 |
| ▸ | GGH | Q92820 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13726857 | 0.88 | NAALAD2 (0.51) | MMP9FOLH1ADAMTS4ADAMTS5NAALAD2 | |
| SCHEMBL4627986 | 0.88 | NAALAD2 (0.51) | MMP9FOLH1ADAMTS4ADAMTS5NAALAD2 | |
| SCHEMBL4627982 | 0.88 | NAALAD2 (0.51) | MMP9FOLH1ADAMTS4ADAMTS5NAALAD2 | |
| SCHEMBL28326846 | 0.87 | KIF11 (0.50) | KIF11FPR2 | |
| SCHEMBL29965194 | 0.87 | KIF11 (0.46) | KIF11KEAP1ADAMTS4ADAMTS5 | |
| SCHEMBL29964852 | 0.87 | KIF11 (0.49) | KIF11KEAP1FPR2 | |
| SCHEMBL4970029 | 0.84 | KIF11 (0.49) | KIF11FPR2 | |
| SCHEMBL7603846 | 0.84 | KIF11 (0.50) | KIF11MMP2MMP9FPR2 | |
| SCHEMBL17274480 | 0.84 | KIF11 (0.50) | KIF11MMP2MMP9FPR2 | |
| SCHEMBL2255754 | 0.83 | NAALAD2 (0.45) | MMP9FOLH1ADAMTS4ADAMTS5NAALAD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4092038-A1 | OPIOID AGONIST PEPTIDES AND USES THEREOF | Protagonist Therapeutics, Inc. (US) | 2022-11-23 | — | — | EP | disclosed |