Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 6/20 | 0.49 |
| ▸ | FPR2 | P25090 | 1/20 | 0.44 |
| ▸ | ACE | P12821 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | LDHA | P00338 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28326846 | 0.90 | KIF11 (0.50) | KIF11FPR2ACEKMT2APPARG | |
| SCHEMBL232515 | 0.87 | NPSR1 (0.44) | ALOX15RECQL | |
| SCHEMBL8682774 | 0.87 | NPSR1 (0.44) | ALOX15RECQL | |
| SCHEMBL232516 | 0.87 | NPSR1 (0.44) | ALOX15RECQL | |
| SCHEMBL29964852 | 0.86 | KIF11 (0.49) | KIF11FPR2KMT2APPARGPPARA | |
| SCHEMBL29964734 | 0.84 | KIF11 (0.50) | KIF11FPR2 | |
| SCHEMBL623398 | 0.82 | ALDH1A1 (0.39) | KIF11FPR2KMT2ANPC1ALDH1A1 | |
| SCHEMBL1487611 | 0.82 | ALDH1A1 (0.39) | KIF11FPR2KMT2ANPC1ALDH1A1 | |
| SCHEMBL10795600 | 0.81 | MDM4 (0.43) | KIF11KMT2AALDH1A1LMNAHSD17B10 | |
| SCHEMBL7603846 | 0.81 | KIF11 (0.50) | KIF11FPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1087992-B1 | ANTITHROMBOTIC COMPOUNDS | ORGANON NV (NL) | 2008-08-20 | — | — | EP | disclosed |
| EP-1087992-A1 | ANTITHROMBOTIC COMPOUNDS | Akzo Nobel N.V. (NL) | 2001-04-04 | — | — | EP | disclosed |
| WO-1999065934-A1 | ANTITHROMBOTIC COMPOUNDS | AKZO NOBEL N.V. (NL) | 1999-12-23 | — | — | WO | disclosed |