⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29965145 | 0.86 | MGLL (0.42) | — | |
| SCHEMBL29964627 | 0.85 | — | — | |
| SCHEMBL29965105 | 0.85 | — | — | |
| SCHEMBL26983410 | 0.84 | SLC6A9 (0.31) | — | |
| SCHEMBL29965175 | 0.83 | KDR (0.32) | — | |
| SCHEMBL26983456 | 0.81 | ALDH1A1 (0.34) | — | |
| SCHEMBL26983404 | 0.81 | ALDH1A1 (0.40) | — | |
| SCHEMBL29964864 | 0.80 | — | — | |
| SCHEMBL26983425 | 0.79 | — | — | |
| SCHEMBL29965177 | 0.79 | DAO (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12600730-B2 | Substituted cyclopenta[c]pyrroles as ABHD6 antagonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 2026-04-14 | — | — | US | disclosed |
| US-20240270755-A1 | SUBSTITUTED CYCLOPENTA[c]PYRROLES AS ABHD6 ANTAGONISTS | ONO PHARMACEUTICAL CO., LTD. (JP) | 2024-08-15 | — | — | US | disclosed |
| EP-4317153-A1 | ABHD6 ANTAGONIST | ONO Pharmaceutical Co., Ltd. (JP) | 2024-02-07 | — | — | EP | disclosed |
| US-20240010658-A1 | ABHD6 ANTAGONIST | ONO PHARMACEUTICAL CO., LTD. (JP) | 2024-01-11 | — | — | US | disclosed |
| WO-2022211060-A1 | ABHD6 ANTAGONIST | 小野薬品工業株式会社 | 2022-10-06 | — | — | WO | disclosed |