Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 6/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | C3AR1 | Q16581 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | BMP1 | P13497 | 3/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | CASR | P41180 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9661340 | 0.90 | C3AR1 (0.43) | KIF11C3AR1CNR1CNR2ITGB3 | |
| SCHEMBL9661344 | 0.90 | C3AR1 (0.43) | KIF11C3AR1CNR1CNR2ITGB3 | |
| Hydrochloric Acid SCHEMBL9659549 | 0.89 | C3AR1 (0.42) | KIF11C3AR1CNR1CNR2ITGB3 | |
| Hydrochloric Acid SCHEMBL9659539 | 0.89 | C3AR1 (0.42) | KIF11C3AR1CNR1CNR2ITGB3 | |
| Hydrochloric Acid SCHEMBL10871326 | 0.84 | NPY4R (0.42) | KIF11C3AR1BMP1 | |
| SCHEMBL17274480 | 0.83 | KIF11 (0.50) | KIF11KCNH2ITGB3ITGA2B | |
| SCHEMBL7603846 | 0.83 | KIF11 (0.50) | KIF11KCNH2ITGB3ITGA2B | |
| SCHEMBL31297047 | 0.81 | MEN1 (0.45) | KIF11KMT2A | |
| SCHEMBL29549032 | 0.81 | KIF11 (0.50) | KIF11KMT2ANPC1RAB9ACNR1 | |
| SCHEMBL29549080 | 0.81 | KIF11 (0.50) | KIF11KMT2ANPC1RAB9ACNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4092038-A1 | OPIOID AGONIST PEPTIDES AND USES THEREOF | Protagonist Therapeutics, Inc. (US) | 2022-11-23 | — | — | EP | disclosed |