Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 9/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | CASR | P41180 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.38 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.38 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.38 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.38 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29549080 | 1.00 | KIF11 (0.50) | KIF11NPC1RAB9ACNR1CNR2 | |
| SCHEMBL31034866 | 1.00 | KIF11 (0.50) | KIF11NPC1RAB9ACNR1CNR2 | |
| SCHEMBL29538792 | 0.89 | KIF11 (0.40) | KIF11CNR1CNR2 | |
| SCHEMBL29864858 | 0.82 | KIF11 (0.55) | KIF11KCNH2 | |
| SCHEMBL29548987 | 0.82 | CTSK (0.43) | KIF11ITGB3ITGA2BHDAC1HDAC7 | |
| SCHEMBL30241772 | 0.81 | KIF11 (0.59) | KIF11NPC1RAB9ACNR1CNR2 | |
| SCHEMBL30241793 | 0.81 | KIF11 (0.59) | KIF11NPC1RAB9ACNR1CNR2 | |
| SCHEMBL30241754 | 0.81 | KIF11 (0.59) | KIF11NPC1RAB9ACNR1CNR2 | |
| SCHEMBL29964865 | 0.81 | KIF11 (0.46) | KIF11NPC1RAB9ACNR1CNR2 | |
| Arginine SCHEMBL29740227 | 0.78 | CA1 (0.48) | KIF11NPC1RAB9ACASRITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4525840-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF HUNTINGTON'S DISEASE AND HTT PROTEINOPATHIES | Stealth BioTherapeutics Inc. (US) | 2025-03-26 | — | — | EP | disclosed |
| CN-118725014-A | Mitochondrial targeting peptides | 隐形生物治疗公司 | 2024-10-01 | — | — | CN | disclosed |
| CN-118702766-A | Mitochondrial targeting peptides | 隐形生物治疗公司 | 2024-09-27 | — | — | CN | disclosed |
| CN-118702767-A | Mitochondrial targeting peptides | 隐形生物治疗公司 | 2024-09-27 | — | — | CN | disclosed |
| CN-111954539-B | Mitochondrial targeting peptides | 隐形生物治疗公司 | 2024-06-21 | — | — | CN | disclosed |
| US-20240092832-A1 | DEUTERATED TETRAPEPTIDES THAT TARGET MITOCHONDRIA | STEALTH BIOTHERAPEUTICS INC. | 2024-03-21 | — | — | US | disclosed |
| US-20240059734-A1 | MITOCHONDRIA-TARGETING PEPTIDES | STEALTH BIOTHERAPEUTICS INC. | 2024-02-22 | — | — | US | disclosed |
| WO-2023224989-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF HUNTINGTON'S DISEASE AND HTT PROTEINOPATHIES | STEALTH BIOTHERAPEUTICS INC. (US) | 2023-11-23 | — | — | WO | disclosed |
| US-11795196-B2 | Mitochondria-targeting peptides | STEALTH BIOTHERAPEUTICS INC. (US) | 2023-10-24 | — | — | US | disclosed |
| EP-4218785-A2 | MITOCHONDRIA-TARGETING PEPTIDES | Stealth BioTherapeutics Inc. (US) | 2023-08-02 | — | — | EP | disclosed |
| US-20230227499-A1 | PRODRUGS OF MITOCHONDRIA-TARGETING OLIGOPEPTIDES | STEALTH BIOTHERAPEUTICS INC. | 2023-07-20 | — | — | US | disclosed |
| US-20230146515-A1 | MITOCHONDRIA-TARGETING PEPTIDES | STEALTH BIOTHERAPEUTICS INC. | 2023-05-11 | — | — | US | disclosed |
| EP-4168424-A1 | PRODRUGS OF MITOCHODRIA-TARGETING OLIGOPEPTIDES | Stealth BioTherapeutics Inc. (US) | 2023-04-26 | — | — | EP | disclosed |
| EP-3723783-B1 | MITOCHONDRIA-TARGETING PEPTIDES | STEALTH BIOTHERAPEUTICS INC (US) | 2023-02-15 | — | — | EP | disclosed |
| EP-3986401-A1 | THE PEPTIDOMIMETIC COMPOUND (R)-2-AMINO-N-((S)-L-(((S)-5-AMINO-L-(3-BENZYL-1,2,4-OXADIAZOL-5-YL)PENTYL)AMINO)-3-(4-HYDROXY-2,6-DIMETHYLPHENYL)-I-OXOPROPAN-2-YL)-5-GUANIDINOPENTANAMIDE IN THE TREATMENT OF NEURODEGENERATIVE DISEASES | Stealth BioTherapeutics Inc. (US) | 2022-04-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230227499-A1 | PRODRUGS OF MITOCHONDRIA-TARGETING OLIGOPEPTIDES | PITRM1, NME4, PDF | KIF11 3101/4885NPC1 1399/4885RAB9A 2023/4885 |
| US-20240092832-A1 | DEUTERATED TETRAPEPTIDES THAT TARGET MITOCHONDRIA | ABAT, SSBP1, PDF | KIF11 2163/4885NPC1 3558/4885RAB9A 3706/4885 |
| US-11795196-B2 | Mitochondria-targeting peptides | HSPE1, TFAM, TNNI3 | KIF11 3536/4885NPC1 2673/4885RAB9A 1631/4885 |
| US-20240059734-A1 | MITOCHONDRIA-TARGETING PEPTIDES | HSPE1, TFAM, TNNI3 | KIF11 3536/4885NPC1 2673/4885RAB9A 1631/4885 |
| US-20230146515-A1 | MITOCHONDRIA-TARGETING PEPTIDES | HSPE1, TFAM, TNNI3 | KIF11 3536/4885NPC1 2673/4885RAB9A 1631/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.