SCHEMBL29965197

SCHEMBL29965197

COc1ccc(C(C(=O)OCC2c3ccccc3-c3ccccc32)(c2ccccc2)c2ccc(OC)cc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ FABP5 Q01469 3/20 0.47
▸ GAA P10253 1/20 0.46
▸ KCNN4 O15554 1/20 0.44
▸ FABP7 O15540 2/20 0.43
▸ MDM2 Q00987 1/20 0.42
▸ KMT2A Q03164 2/20 0.41
▸ KIF11 P52732 4/20 0.41
▸ MDM4 O15151 1/20 0.41
▸ TP53 P04637 1/20 0.41
▸ EDNRB P24530 1/20 0.40
▸ EDNRA P25101 1/20 0.40
▸ ALDH1A1 P00352 1/20 0.39
▸ HTT P42858 1/20 0.39
▸ EPHX2 P34913 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29398623 0.89 FABP5 (0.51) FABP5KCNN4FABP7KMT2AMDM4
SCHEMBL9224988 0.82 FABP5 (0.43) FABP5GAAFABP7MDM2KMT2A
SCHEMBL1311053 0.79 FABP5 (0.44) FABP5GAAFABP7MDM2KMT2A
SCHEMBL12061892 0.77 MDM2 (0.49) FABP5GAAMDM2KMT2AKIF11
SCHEMBL14946789 0.77 FABP5 (0.41) FABP5GAAFABP7MDM2KMT2A
SCHEMBL7801461 0.77 KMT2A (0.52) FABP5GAAMDM2KMT2AMDM4
SCHEMBL28069714 0.77 FABP5 (0.45) FABP5FABP7MDM2KMT2AKIF11
SCHEMBL27597924 0.76 CHRM2 (0.52) FABP5FABP7KMT2AMDM4TP53
SCHEMBL30990574 0.76 NPC1 (0.52) FABP5KCNN4FABP7KIF11ALDH1A1
SCHEMBL27597932 0.75 FABP5 (0.46) FABP5FABP7KMT2AMDM4TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250002531-A1 PROCESSES FOR PREPARING PHARMACEUTICALLY RELEVANT PEPTIDES STEALTH BIOTHERAPEUTICS INC. (US) 2025-01-02 — — US disclosed
CN-118725014-A Mitochondrial targeting peptides 隐形生物治疗公司 2024-10-01 — — CN disclosed
CN-118702766-A Mitochondrial targeting peptides 隐形生物治疗公司 2024-09-27 — — CN disclosed
CN-118702767-A Mitochondrial targeting peptides 隐形生物治疗公司 2024-09-27 — — CN disclosed
US-12037414-B2 Processes for preparing pharmaceutically relevant peptides STEALTH BIOTHERAPEUTICS INC. (US) 2024-07-16 — — US disclosed
EP-3862431-B1 METHOD FOR PRODUCING HAIRPIN SINGLE-STRAND RNA MOLECULES TORAY INDUSTRIES (JP) 2024-06-26 — — EP disclosed
CN-111954539-B Mitochondrial targeting peptides 隐形生物治疗公司 2024-06-21 — — CN disclosed
US-20240110186-A1 METHOD OF PRODUCING HAIRPIN SINGLE-STRANDED RNA MOLECULES TORAY INDUSTRIES, INC. (JP) 2024-04-04 — — US disclosed
US-20240059734-A1 MITOCHONDRIA-TARGETING PEPTIDES STEALTH BIOTHERAPEUTICS INC. 2024-02-22 — — US disclosed
US-11891602-B2 Method of producing hairpin single-stranded RNA molecules TORAY INDUSTRIES, INC. (JP) 2024-02-06 — — US disclosed
US-11795196-B2 Mitochondria-targeting peptides STEALTH BIOTHERAPEUTICS INC. (US) 2023-10-24 — — US disclosed
EP-4218785-A2 MITOCHONDRIA-TARGETING PEPTIDES Stealth BioTherapeutics Inc. (US) 2023-08-02 — — EP disclosed
US-20230146515-A1 MITOCHONDRIA-TARGETING PEPTIDES STEALTH BIOTHERAPEUTICS INC. 2023-05-11 — — US disclosed
EP-3723783-B1 MITOCHONDRIA-TARGETING PEPTIDES STEALTH BIOTHERAPEUTICS INC (US) 2023-02-15 — — EP disclosed
EP-4092038-A1 OPIOID AGONIST PEPTIDES AND USES THEREOF Protagonist Therapeutics, Inc. (US) 2022-11-23 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250002531-A1 PROCESSES FOR PREPARING PHARMACEUTICALLY RELEVANT PEPTIDES ADM2, VIP, PEPD FABP5 4568/4885GAA 1903/4885KCNN4 3649/4885
US-11795196-B2 Mitochondria-targeting peptides HSPE1, TFAM, TNNI3 FABP5 440/4885GAA 1795/4885KCNN4 3760/4885
US-12037414-B2 Processes for preparing pharmaceutically relevant peptides ADM2, VIP, PEPD FABP5 4568/4885GAA 1903/4885KCNN4 3649/4885
US-20240059734-A1 MITOCHONDRIA-TARGETING PEPTIDES HSPE1, TFAM, TNNI3 FABP5 440/4885GAA 1795/4885KCNN4 3760/4885
US-20230146515-A1 MITOCHONDRIA-TARGETING PEPTIDES HSPE1, TFAM, TNNI3 FABP5 440/4885GAA 1795/4885KCNN4 3760/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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