SCHEMBL29965245

SCHEMBL29965245

O=C1NC(c2ccccc2)c2cc(Cl)ccc2O1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 1/20 0.45
LMNA P02545 3/20 0.44
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
MAPT P10636 1/20 0.44
CHRM2 P08172 1/20 0.42
HTR1A P08908 1/20 0.42
ADRA2A P08913 1/20 0.42
DRD2 P14416 1/20 0.42
GABRA1 P14867 1/20 0.42
ADRA2B P18089 1/20 0.42
ADRA2C P18825 1/20 0.42
DRD1 P21728 1/20 0.42
DRD4 P21917 1/20 0.42
SLC6A2 P23975 1/20 0.42
ADRA1D P25100 1/20 0.42
HTR2A P28223 1/20 0.42
HTR2C P28335 1/20 0.42
SLC6A4 P31645 1/20 0.42
ADRA1A P35348 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16109479 0.82 SIRT2 (0.45) CYP19A1LMNAMEN1KMT2AMAPT
SCHEMBL29965150 0.81 MAPT (0.65) CYP19A1LMNAMEN1KMT2AMAPT
SCHEMBL10481347 0.74 GAA (0.68) CYP19A1MEN1KMT2AMAPTCHRM2
SCHEMBL9228116 0.73 ALDH1A1 (0.70) CYP19A1MEN1KMT2AMAPTGAA
SCHEMBL31357878 0.73 CYP19A1 (0.45) CYP19A1LMNAMEN1KMT2AMAPT
SCHEMBL23088788 0.73 CYP19A1 (0.42) CYP19A1LMNAMEN1KMT2ACHRM2
SCHEMBL16109308 0.72 BRD4 (0.67)
SCHEMBL11643617 0.71 PRCP (0.43) CYP19A1ADRA2ADRD2DRD1HTR2A
SCHEMBL4195064 0.70 MAPT (0.42) LMNAMEN1KMT2AMAPTGAA
SCHEMBL4195063 0.70 MAPT (0.42) LMNAMEN1KMT2AMAPTGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110372625-B Method for preparing 4-alkyl methyl-4-aryl-1,3-benzoxazine-2 (4H) -ketone by blue light irradiation 常州大学 2022-11-01 CN disclosed