SCHEMBL29965150

SCHEMBL29965150

O=C1NC(c2ccccc2)c2ccccc2O1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.65
KMT2A Q03164 2/20 0.65
MEN1 O00255 1/20 0.65
LMNA P02545 1/20 0.65
PRCP P42785 1/20 0.40
GAA P10253 4/20 0.39
MAOB P27338 2/20 0.38
MAOA P21397 1/20 0.38
HSD17B10 Q99714 3/20 0.38
ALDH1A1 P00352 3/20 0.38
HPGD P15428 2/20 0.38
KDM4E B2RXH2 2/20 0.38
CYP2C9 P11712 2/20 0.38
GFER P55789 1/20 0.38
ADORA3 P0DMS8 1/20 0.38
AR P10275 1/20 0.38
CYP19A1 P11511 1/20 0.38
USP2 O75604 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
CA2 P00918 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16109479 0.81 SIRT2 (0.45) MAPTKMT2AMEN1LMNAGAA
SCHEMBL29965245 0.81 CYP19A1 (0.45) MAPTKMT2AMEN1LMNAGAA
SCHEMBL17844951 0.78 LMNA (0.42) MAPTKMT2AMEN1LMNAGAA
SCHEMBL4195063 0.77 MAPT (0.42) MAPTKMT2AMEN1LMNAPRCP
SCHEMBL4195064 0.77 MAPT (0.42) MAPTKMT2AMEN1LMNAPRCP
SCHEMBL18268190 0.77 MAPT (0.43) MAPTKMT2AMEN1LMNAGAA
SCHEMBL18268206 0.77 ALDH1A1 (0.52) MAPTKMT2AMEN1LMNAGAA
SCHEMBL11265304 0.76 MAPT (0.41) MAPTKMT2AMEN1LMNAPRCP
SCHEMBL632326 0.70 KMT2A (0.41) MAPTKMT2AMEN1LMNAMAOB
SCHEMBL31087316 0.69 MEN1 (0.53) MAPTKMT2AMEN1LMNAPRCP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110372625-B Method for preparing 4-alkyl methyl-4-aryl-1,3-benzoxazine-2 (4H) -ketone by blue light irradiation 常州大学 2022-11-01 CN disclosed