Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.36 |
| ▸ | PRCP | P42785 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4195063 | 1.00 | MAPT (0.42) | MAPTKMT2AALDH1A1GAAKDM4E | |
| SCHEMBL11265304 | 0.98 | MAPT (0.41) | MAPTKMT2AALDH1A1GAAKDM4E | |
| SCHEMBL164001 | 0.80 | TDP1 (0.50) | KMT2AGAAPRCP | |
| SCHEMBL31357816 | 0.77 | KMT2A (0.65) | MAPTKMT2AALDH1A1GAAKDM4E | |
| SCHEMBL29965150 | 0.77 | MAPT (0.65) | MAPTKMT2AALDH1A1GAAKDM4E | |
| SCHEMBL7218139 | 0.72 | IDO1 (0.38) | — | |
| SCHEMBL31357782 | 0.71 | LMNA (0.42) | MAPTKMT2AALDH1A1KDM4EHSD17B10 | |
| Methane SCHEMBL11336749 | 0.70 | MAPT (0.48) | MAPTKMT2AALDH1A1GAAKDM4E | |
| SCHEMBL1895535 | 0.70 | MAPT (0.48) | MAPTKMT2AALDH1A1GAAKDM4E | |
| SCHEMBL1894049 | 0.70 | MAPT (0.48) | MAPTKMT2AALDH1A1GAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4489208-A | Process for producing D(-)mandelic acid | E.N.I. NAZIONALE IDROCARBURI (IT) | 1984-12-18 | — | — | US | claimed |
| WO-2024028255-A1 | POLY(AMINO ACID) BASED CAPSULES | AGFA-GEVAERT NV (BE) | 2024-02-08 | — | — | WO | disclosed |
| US-20150060361-A1 | DRAW SOLUTES INCLUDING AMINO ACID IONIC OLIGOMERS | LOTTE CHEMICAL CORPORATION (KR) | 2015-03-05 | — | — | US | disclosed |
| US-7498431-B2 | Process for the preparation of chiral azetidinones | FRAMROZE BOMI PATEL | 2009-03-03 | — | — | US | disclosed |
| US-7482368-B2 | Triamide-substituted heterobicyclic compounds | PFIZER INC (US) | 2009-01-27 | — | — | US | disclosed |
| EP-1404653-B1 | TRIAMIDE-SUBSTITUTED INDOLES, BENZOFURANES AND BENZOTHIOPHENES AS INHIBITORS OF MICROSOMAL TRIGLYCERIDE TRANSFER PROTEIN (MTP) AND/OR APOLIPOPROTEIN B (APO B) SECRETION | PFIZER PROD INC (US) | 2008-08-20 | — | — | EP | disclosed |
| US-7348355-B2 | Treating obesity with the Microsomal triglyceride transfer protein inhibitor (S) N-{2-[benzyl(methyl)amino]-2-oxo-1-phenylethyl}-1-methyl-5-[4'-(trifluoromethyl)[1,1'-biphenyl]-2-carboxamido]-1H-indole-2-carboxamide and another lipid lowering agent such as a statin or fibrate | PFIZER INC. (US) | 2008-03-25 | — | — | US | disclosed |
| US-20070129540-A1 | Process for the preparation of chiral azetidinones | OPUS ORGANICS PVT LIMITED (IN) | 2007-06-07 | — | — | US | disclosed |
| US-20060194772-A1 | Triamide-substituted heterobicyclic compounds | PFIZER INC | 2006-08-31 | — | — | US | disclosed |
| US-7002008-B2 | Process for the preparation of 1-(4-fluorophenyl)-4(S)-(4-hydroxyphenyl)-azetidin-2-one | FRAMROZE BOMI PATEL | 2006-02-21 | — | — | US | disclosed |
| US-5744471-A | NERVOUS SYSTEM DISORDERS | ZENECA LIMITED (GB) | 1998-04-28 | — | — | US | disclosed |
| CN-1171787-A | Pyridazinoquinoline compounds | ZENECA LTD (GB) | 1998-01-28 | — | — | CN | disclosed |
| EP-0790996-A1 | PYRIDAZINOQUINOLINE COMPOUNDS | ZENECA LIMITED (GB) | 1997-08-27 | — | — | EP | disclosed |
| CN-1138332-A | Pyridazinoquinoline compounds | ZENECA LTD (GB) | 1996-12-18 | — | — | CN | disclosed |
| EP-0724583-A1 | PYRIDAZINO QUINOLINE COMPOUNDS | ZENECA LIMITED (GB) | 1996-08-07 | — | — | EP | disclosed |
| WO-1996015127-A1 | PYRIDAZINOQUINOLINE COMPOUNDS | ZENECA LIMITED (GB) | 1996-05-23 | — | — | WO | disclosed |
| WO-1995011244-A1 | PYRIDAZINO QUINOLINE COMPOUNDS | ZENECA LIMITED (GB) | 1995-04-27 | — | — | WO | disclosed |
| US-4489208-A | Process for producing D(-)mandelic acid | E.N.I. NAZIONALE IDROCARBURI (IT) | 1984-12-18 | — | — | US | disclosed |
| US-4332905-A | STEREOSELECTIVE ENZYMATIC HYDROLYSIS OF RACEMIC 5-SUBSTITUTED 2,4-OXAZOLIDINEDIONES | E.N.I. ENTE NOZIONALE IDROCARBURI (IT) | 1982-06-01 | — | — | US | disclosed |
| US-4314023-A | AZO-METHINE DYES | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1982-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060194772-A1 | Triamide-substituted heterobicyclic compounds | APOB, LIPC, MTTP | MAPT 3447/4885KMT2A 2232/4885ALDH1A1 3734/4885 |
| US-20070129540-A1 | Process for the preparation of chiral azetidinones | CYP1B1, ALDH7A1, CYP3A5 | MAPT 4388/4885KMT2A 4551/4885ALDH1A1 79/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.