Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | THRA | P10827 | 2/20 | 0.36 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | ALPL | P05186 | 2/20 | 0.34 |
| ▸ | STAT3 | P40763 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23671355 | 1.00 | MAPT (0.38) | MAPTSMN1; SMN2HPGDLMNACYP2C9 | |
| SCHEMBL23691224 | 0.88 | L3MBTL1 (0.37) | MAPTSMN1; SMN2HPGDLMNACYP2C9 | |
| SCHEMBL29964531 | 0.88 | L3MBTL1 (0.37) | MAPTSMN1; SMN2HPGDLMNACYP2C9 | |
| SCHEMBL23691262 | 0.83 | MAPT (0.41) | MAPTSMN1; SMN2HPGDLMNACYP2C9 | |
| SCHEMBL29965518 | 0.83 | TRPV4 (0.38) | MAPTSMN1; SMN2TRPV4ALDH1A1POLB | |
| SCHEMBL23663269 | 0.83 | TRPV4 (0.38) | MAPTSMN1; SMN2TRPV4ALDH1A1POLB | |
| SCHEMBL26401753 | 0.82 | MAPT (0.40) | MAPTSMN1; SMN2HPGDLMNACYP2C9 | |
| SCHEMBL23663412 | 0.82 | SMN1; SMN2 (0.46) | SMN1; SMN2HPGDLMNAALDH1A1MAPK1 | |
| SCHEMBL23691382 | 0.79 | MAPT (0.38) | MAPTSMN1; SMN2HPGDLMNACYP2C9 | |
| SCHEMBL7208834 | 0.79 | PDE7A (0.42) | MAPTSMN1; SMN2HPGDLMNACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115244037-B | Substituted triazinones as thyroid hormone receptor agonists | 诚益生物(美国)公司 | 2024-10-25 | — | — | CN | disclosed |
| EP-4090652-A1 | SUBSTITUTED TRIAZINONES AS THYROID HORMONE RECEPTOR AGONISTS | Eccogene (Shanghai) Co., Ltd. (CN) | 2022-11-23 | — | — | EP | disclosed |
| CN-115244037-A | Substituted triazinones as thyroid hormone receptor agonists | 上海诚益生物科技有限公司 | 2022-10-25 | — | — | CN | disclosed |