Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 3/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2224694 | 1.00 | ESR1 (0.44) | ESR1ESR2ALDH1A1KDM4EHSD17B10 | |
| Hydrochloric Acid SCHEMBL4557118 | 0.98 | ESR1 (0.43) | ESR1ESR2ALDH1A1KDM4EHSD17B10 | |
| Hydrochloric Acid SCHEMBL14576584 | 0.98 | ESR1 (0.43) | ESR1ESR2ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL11797881 | 0.78 | PLA2G2A (0.43) | ESR1ESR2ALDH1A1KDM4EPARP1 | |
| SCHEMBL983399 | 0.76 | ESR1 (0.61) | ESR1ESR2ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL14576583 | 0.75 | MAP2 (0.40) | ESR1ESR2ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL11790809 | 0.75 | ALDH1A1 (0.44) | ALDH1A1KDM4ESMN1; SMN2PARP1MAPT | |
| SCHEMBL4953231 | 0.74 | ALDH1A1 (0.42) | ESR1ESR2ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL31550430 | 0.74 | PSMB8 (0.38) | ALDH1A1KDM4EHSD17B10GAAHPGD | |
| SCHEMBL3873727 | 0.73 | PSMB8 (0.43) | ALDH1A1KDM4EHSD17B10GAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11484571-B2 | Pharmaceutical compositions containing beta-2 microglobulin and methods of treating autoimmune diseases | BETA INNOV (FR) | 2022-11-01 | — | — | US | disclosed |