Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 3/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.40 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.37 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.37 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.37 |
| ▸ | MAP2 | P11137 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28213843 | 0.84 | CLK4 (0.46) | ALDH1A1HSD17B10HPGDCA1CA2 | |
| SCHEMBL27679926 | 0.78 | CYP19A1 (0.38) | ALDH1A1HSD17B10HPGDEGFRESR1 | |
| SCHEMBL2224694 | 0.74 | ESR1 (0.44) | ALDH1A1HSD17B10HPGDESR1ESR2 | |
| SCHEMBL29965835 | 0.74 | ESR1 (0.44) | ALDH1A1HSD17B10HPGDESR1ESR2 | |
| SCHEMBL31550430 | 0.74 | PSMB8 (0.38) | ALDH1A1HSD17B10HPGDKDM4EMAPT | |
| Hydrochloric Acid SCHEMBL14576584 | 0.73 | ESR1 (0.43) | ALDH1A1HSD17B10HPGDESR1ESR2 | |
| Hydrochloric Acid SCHEMBL4557118 | 0.73 | ESR1 (0.43) | ALDH1A1HSD17B10HPGDESR1ESR2 | |
| SCHEMBL3873727 | 0.73 | PSMB8 (0.43) | ALDH1A1HSD17B10HPGDKDM4EMAPT | |
| SCHEMBL10939474 | 0.70 | CLK4 (0.47) | ALDH1A1HSD17B10HPGDMAPTPARP1 | |
| SCHEMBL5754263 | 0.70 | ALDH1A1 (0.55) | ALDH1A1HSD17B10HPGDMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008045952-A2 | PHOTORECEPTOR PRECURSOR CELLS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2008-04-17 | — | — | WO | disclosed |