Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 8/20 | 0.41 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.40 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | TOP1 | P11387 | 1/20 | 0.39 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 2/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | ERN1 | O75460 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29966580 | 0.79 | BACE1 (0.45) | ALKDYRK1APIK3CA | |
| SCHEMBL9196002 | 0.79 | BACE1 (0.45) | ALKDYRK1APIK3CA | |
| SCHEMBL29966762 | 0.74 | DYRK1A (0.38) | DYRK1APIK3CA | |
| SCHEMBL29967067 | 0.72 | BACE1 (0.51) | CLK4DYRK1ACCNE2CCNE1CDK2 | |
| SCHEMBL26259745 | 0.72 | PGR (0.62) | PGRTOP1PIK3R1PIK3CAPIM1 | |
| SCHEMBL29966792 | 0.70 | CYP1A2 (0.43) | — | |
| SCHEMBL28874637 | 0.70 | BACE1 (0.41) | PIM1ERN1 | |
| SCHEMBL28874626 | 0.70 | CYP1A2 (0.43) | — | |
| SCHEMBL9190130 | 0.70 | TYMS (0.40) | HRH4 | |
| SCHEMBL29966934 | 0.70 | BACE1 (0.41) | PIM1ERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115260122-B | Naphthothiazole derivative and synthesis method thereof | 陕西科技大学 | 2024-05-28 | — | — | CN | disclosed |
| CN-115260122-A | Naphthothiazole derivative and synthesis method thereof | 陕西科技大学 | 2022-11-01 | — | — | CN | disclosed |